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Gene therapy in the womb: a new hope for babies with fatal brain disease

NCT ID NCT07479953

First seen Mar 20, 2026 · Last updated Jun 12, 2026 · Updated 13 times

Summary

This study tests a one-time gene therapy given directly to the fetus through the mother's bloodstream before birth. It is for babies diagnosed with GM1 gangliosidosis, a severe genetic disorder that damages the brain and body. The goal is to see if the treatment is safe and can help control the disease by providing a working copy of the missing enzyme. Only 5 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

GM1 gangliosidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.