Pregnancy pain mystery: scientists probe body signals and stress
NCT ID NCT04226716
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 192 women who have been pregnant before to learn why some develop pelvic or lower back pain during pregnancy and after childbirth. Researchers will measure body awareness, stress, anxiety, and inflammation to see how these factors relate to pain and balance. The goal is to find better ways to prevent or treat this common pregnancy problem.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 192 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2020
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria Multiparous Women: * Singleton pregnancy * Pregnant of second child or more than second child * No current PPGP or did not have PPGP during current pregnancy * Willing to provide written informed consent Exclusion Criteria Multiparous Women: * Pregnant for more than 16 weeks * Having current PPGP or having had PPGP during the current pregnancy * History of surgery/major trauma to spine or pelvis * Surgery/physical trauma to the lower limbs more than two years ago and currently still experiencing symptoms such as pain, instability, or stiffness * Surgery/physical trauma to the lower limbs less than two years ago * Specific balance or vestibular disorders * A medical diagnosis of a rheumatic condition or being under treatment for such a condition by a rheumatologist * Neurological abnormalities (e.g., peripheral neuropathy) * Uncorrected visual problems * Acute ankle problems * Being on absolute or relative bed rest due to pregnancy-related complications * Having (had) a formal diagnosis of a psychiatric disorder * Non-Dutch speaking Inclusion Criteria Nulliparous Women: * Age- and BMI- matched to pregnant participants * Nulliparous * Willing to provide written informed consent Exclusion Criteria Nulliparous Women: * Having low back or pelvic girdle pain at the time of inclusion or in the six months leading up to inclusion * History of chronic low back or pelvic girdle pain * History of surgery/major trauma to spine, pelvis and/or lower limbs, * Specific balance or vestibular disorders * Spinal deformities * Rheumatic disease * Neurological abnormalities * Acute ankle problems * (A history of) psychiatric disorders * Uncorrected visual problems * Non-Dutch speaking
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hasselt University
RECRUITINGHasselt, 3590, Belgium
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