Ultrasound duo may predict ventilator weaning failure
NCT ID NCT07702422
First seen Jul 14, 2026 · Last updated Sep 18, 2026 · Updated 4 times
Summary
This study tests whether combining two ultrasound measurements—parasternal intercostal muscle thickening and diaphragmatic movement—can predict which patients will fail when taken off a breathing machine. Researchers will measure these in 70 adults who have been on mechanical ventilation for over 48 hours. The goal is to find a quick, non-invasive way to avoid both premature and delayed removal of the breathing tube.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could give doctors a simple bedside tool to better decide when to safely remove a breathing tube, reducing complications.
- What could go wrong
- This is a small, early observational study. The ultrasound method may not prove accurate enough in larger, more diverse groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
* All the patients with difficulty in obtaining an appropriate ultrasound window (diaphragmatic paralysis/injury, ascites, thoracotomy, pneumothorax, pleural effusion, flail chest, and rib fractures). * Neuromuscular diseases. * Severe head injury. * Pregnant and lactating women.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years old. * Both sexes. * Patients who have been mechanically ventilated for more than 48 h. Exclusion Criteria: * All the patients with difficulty in obtaining an appropriate ultrasound window (diaphragmatic paralysis/injury, ascites, thoracotomy, pneumothorax, pleural effusion, flail chest, and rib fractures). * Neuromuscular diseases. * Severe head injury. * Pregnant and lactating women.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.