New study aims to predict recovery in children with brain injury
NCT ID NCT07538440
First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 2 times
Summary
This study is working to create a prediction model specifically for children with moderate to severe traumatic brain injury (TBI). Currently, doctors use models designed for adults, which may not be accurate for kids. Researchers will analyze data from 2000 children to develop a more reliable tool for predicting outcomes and guiding treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a more accurate tool for predicting recovery in children with traumatic brain injury, helping doctors make better treatment decisions and inform families.
- What could go wrong
- This is an observational study that builds on existing models, not a test of a new treatment. The new prediction model may not be significantly better than current adult models.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The existing datasets of paediatric patients with moderate to severe TBI will be combined and prediction model will be developed using the baseline injury severity variables with training and validation groups.
- Ages
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Up to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients admitted to hospital with moderate to severe TBI Exclusion Criteria: * None
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital
Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom
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Other studies related to the condition(s) this trial covers.
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