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Breath test may warn of kidney danger in ICU

NCT ID NCT07654010

Knowledge-focused Sponsor: Malatya Egitim Ve Arastirma Hastanesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 155 critically ill patients on ventilators to see if the difference between carbon dioxide in their breath and blood could predict acute kidney injury. Researchers measured this gap over the first 24 hours in the ICU. The goal was to find a simple, early warning sign for kidney problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive way to spot kidney trouble early in ventilated ICU patients.
What could go wrong
This is a small, completed observational study, not a treatment trial. The findings may not apply to all patients or lead to a proven clinical tool.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

155 people

The number who actually took part.

Started

Mar 2026

Finished

Jun 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients being monitored with mechanical ventilators in intensive care

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years of age * patients under mechanical ventilation * initiation of EtCO₂ monitoring within the first hour of admission to the ICU * patients monitored in the ICU for at least 24 hours * having undergone arterial blood gas analysis (for PaCO₂ measurement) within the first 24 hours. Exclusion Criteria: * Patients under 18 years of age * intensive care unit monitoring shorter than 24 hours * missing or inaccessible clinical data * chronic renal failure * acute renal failure present at admission to intensive care unit * advanced pulmonary diseases affecting EtCO₂ measurement (e.g., severe obstruction, giant bulla, advanced emphysema) * patients in whom PaCO₂ measurement cannot be performed

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury Ventilated patient in intensive care

Contacts and locations

Locations

  • Malatya Training and Research Hospital

    Malatya, Osmaniye, +90(505)620-3888, Turkey (Türkiye)

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