New tests could help spot hidden blood disorder in seniors
NCT ID NCT01648556
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study followed 37 adults over age 60 with unexplained low platelet counts to see if certain tests could predict immune thrombocytopenic purpura (ITP). Participants had blood tests, bone marrow biopsies, and a short course of the steroid prednisone. The goal was to find which tests best point to ITP, helping doctors avoid unnecessary procedures and start the right treatment sooner.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- prednisone
- What this could lead to
- If successful, this could help doctors better diagnose immune thrombocytopenia in older adults, leading to more targeted treatment.
- What could go wrong
- This is a small, completed study with only 37 participants. The results may not apply to all patients, and the tests studied might not be reliable enough for routine use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
37 people
The number who actually took part.
- Started
-
Jan 2013
- Finished
-
Dec 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
60 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Rate of platelet \< 100 G/l for less than 12 months , * age = ou \> 60 years, * haemoglobin \> ou = 12 g / dl at the woman, \> ou = 13 g/dl at the man, * polymorphonuclear neutrophil \> ou = 1.7 G/l, * monocytes \< ou= 1 G/l, * lymphocytes \< ou = à 4 G/l, * VGM \< 100 fL, blood film normal, * informed consent, * expectation of life \> 6 months Exclusion Criteria: * hepatomegaly, * splenomegaly, * hepatic abnormality, * blood coagulation abnormality, * antecedent of auto-immune disease, * drug thrombopenia, * HIV, VHB or VHC positive, * antecedent of malicious tumor in the 5 years before inclusion
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens
Amiens, 80000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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