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Simple blood test may predict Post-Surgery confusion in colorectal cancer patients

NCT ID NCT07597330

Knowledge-focused Sponsor: LanZhou University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 590 colorectal cancer patients to develop a risk tool that predicts postoperative delirium—a common complication causing confusion and slower recovery. Researchers combined blood test results (including the TyG index) with patient subtypes to create a scoring system. The goal is to help doctors quickly spot high-risk patients and provide targeted care, though this is only a data-collection study and does not test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple way to identify patients at high risk for confusion after colorectal cancer surgery, allowing for earlier preventive care.
What could go wrong
This is an observational study that only collects data, so it does not test a new treatment. The risk tool may not be accurate enough for routine use and needs further validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

590 people

The number who actually took part.

Started

Jan 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will be selected from patients who present to the First Hospital of Lanzhou University, and are scheduled for elective surgical resection of histologically confirmed colorectal cancer\*\*. Eligible participants will be consecutively recruited during the study period, with selection strictly adhering to predefined inclusion and exclusion criteria to ensure homogeneity and relevance to the research objective of developing a colorectal cancer-specific postoperative delirium risk prediction tool.

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Histologically confirmed colorectal cancer (colon or rectal cancer) via - preoperative or postoperative pathology; * Scheduled for elective surgical intervention (open or laparoscopic resection); * Preoperative Mini Mental State Examination (MMSE) score ≥18 (no pre-existing cognitive impairment); * Able to provide written informed consent (self or legal representative); * Complete preoperative clinical and laboratory data. Exclusion Criteria: * Postoperative pathology confirmed non-malignant tumor; * Age ≥90 years old; * Presence of visual, cognitive, language, or speech impairment; or history of neuropsychiatric diseases (dementia, Parkinson's disease, cerebrovascular accidents); * No preoperative cognitive function assessment or MMSE score \<18; * Emergency surgery or palliative surgery (non-curative resection); * Postoperative admission to intensive care unit (ICU) (excluded due to different monitoring and intervention patterns); * Missing key data \>5% (e.g., incomplete TyG index calculation, missing clustering analysis variables); * Refusal to participate or inability to complete 7-day postoperative follow-up.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer (msi-H) Postoperative delirium (POD)

Contacts and locations

Locations

  • The first hospital of lanzhou university

    Lanzhou, Gansu, 73000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.