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Can a tailored lifestyle plan outsmart Obesity-Related health risks?

NCT ID NCT07742917

Prevention Sponsor: Institute for Healthier Living Abu Dhabi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial tests whether a personalized lifestyle medicine program can improve cardiometabolic health in Emirati adults aged 25-50 with obesity. Participants receive an 18-week program tailored to their individual health screening results, with follow-up over 24 weeks. The study compares them to a similar group receiving standard care to see if the personalized approach leads to greater improvements in weight, blood sugar, cholesterol, and blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Precision Lifestyle Medicine Program (behavioral intervention)
What this could lead to
If successful, this could show that personalized lifestyle coaching based on individual health screening can meaningfully reduce risks for heart disease and type 2 diabetes in people with obesity.
What could go wrong
This is a relatively small, early-stage trial, and the program's success depends on participants sticking with lifestyle changes. Results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Emiratis residing in Abu Dhabi emirate * Aged 25-50 years * BMI 30-35 kg/m² * Thiqa cardholder * Previous participation in IFHAS screening * Able to provide informed consent * Participant in the Emirati Genome Programme * No weight-loss medications (e.g., Ozempic, Saxenda, Wegovy) within 3 months of enrollment. Exclusion Criteria: * Aged under 25 years or over 50 years of age * BMI range under 30 kg/m2 and over 35 kg/m2 * Taking weight loss medication such as GLP-1 drugs (Ozempic, Saxenda, Wegovy) * Active treatment for serious medical conditions (cancer, planned surgery, immunomodulation) * Transplant surgery within 12 months * Pregnancy * Surgery within 3 months prior to recruitment * Physical limitations preventing exercise participation * Current enrolment in other lifestyle intervention programs * Active psychiatric conditions, cognitive impairment, or mental health conditions affecting study participation * Contraindication to MRI or DEXA imaging, including severe claustrophobia or need for sedation.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bmi/body composition Cardiometabolic risk Cardiovascular disease risk Obese adults Type 2 diabetes risk

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Institute for Healthier Living

    RECRUITING

    Abu Dhabi, United Arab Emirates

More trials for these conditions

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