Fizzy science: do prebiotic sodas beat regular soda on hunger and blood sugar?
NCT ID NCT07105826
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how four different drinks—two prebiotic sodas, regular Coca-Cola, and Diet Coke—affect hunger, blood sugar, insulin, and appetite hormones in healthy men aged 18-40. Ten participants visited the lab four times, each time drinking one of the beverages in a random order after fasting. The goal was to see if prebiotic sodas offer any benefits over sugary or diet sodas for appetite and metabolic health.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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10 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Gender: Male * Age: 18-40 years * Health Status: Healthy, with no significant medical conditions * Body Mass Index (BMI): 18.5-24.9 kg/m² Exclusion Criteria * Diabetes: Diagnosed diabetes (Type 1 or Type 2) * Gastrointestinal Disorders: Any diagnosed gastrointestinal conditions (e.g., irritable bowel syndrome, inflammatory bowel disease) * Liver Disease: Any diagnosed liver conditions * Kidney Disease: Any diagnosed kidney conditions * Cardiovascular Disease: Any diagnosed cardiovascular conditions * Hypertension: Diagnosed high blood pressure * Recent Illness or Infection: Any illness or infection within the past 30 days that could affect study outcomes * Tobacco or Nicotine Use: Current use of tobacco or nicotine products (e.g., smoking, vaping) * Phenylketonuria (PKU): A genetic disorder affecting phenylalanine metabolism, due to the presence of aspartame in Diet Coke * Medication Use: Use of medications or supplements that affect glucose metabolism, insulin response, or appetite * Intermittent Fasting: Engagement in intermittent fasting or inconsistent time-restricted feeding patterns * Other Health Conditions: Any other health conditions that, in the opinion of the investigators, could interfere with study participation or outcomes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Texas Christian University
Fort Worth, Texas, 76180, United States