New Pre-Workout powder put to the test: does it boost endurance and mood?
NCT ID NCT07225608
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a new pre-workout supplement can improve endurance, strength, mood, and energy in healthy adults. Twenty-seven participants took either the supplement or a placebo before exercise tests. Researchers measured cycling endurance, bench press performance, and self-reported mood and energy levels. The goal is to see if the supplement offers real benefits for exercise.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- proprietary pre-workout supplement
- What this could lead to
- If it works, this could show that the supplement helps improve exercise performance and energy in healthy adults.
- What could go wrong
- This is a small, completed study with only 27 participants. Results may not apply to everyone, and the supplement's effects could be similar to placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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27 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Feb 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy males or females aged 18-55 * Must be recreationally trained or trained/developmental as previously defined (McKay et al., 2021) * Able to read and write in English * Willing to maintain their regular supplement routine during the study (other than what is listed in exclusion criteria) * Are not consistently taking, or will discontinue consuming other pre-workout supplements or dietary supplements, such as creatine, rhodiola, L-Theanine, glycerol, stimulants other than caffeine, or ingredients which may promote hydration or enhance physical performance within the past 2-weeks, and throughout the duration of the study. * Willing to restrict caffeine for 24 hours prior to testing * Will not participate in any strenuous exercise for a minimum of 72 hours prior to exercise performance assessments. Strenuous exercise as defined for this study includes ½ and full marathons (or more), heavy (i.e.,\>80% 1RM) lifting, and any high intensity, physical activity that could make your muscles sore. Exclusion Criteria: * Sedentary: Individuals performing less than 150 minutes of moderate or 75 minutes of vigorous activity per week and engaging in resistance training fewer than 2 days per week, with no structured exercise routine. * Highly trained/national level or professional athlete: Individuals training ≥5 days per week in structured programs, including NCAA Division II/III athletes, national/professional competitors, or those targeting top 20% sport-specific performance norms. * Known diagnosis of any cardiovascular, metabolic, endocrine, or renal disease * Recent musculoskeletal injury (\<3-months) * Recent orthopaedic surgery (\<12-months) * History or current malignancy * Previous gastrointestinal surgery within the past 12 months * Regular smoker * Regular drinker (\>14 drinks per week) * Current respiratory infection (i.e. cold) or high temperature (fever) within the past 4-weeks * Presently using GLP-1 medications * Individuals with cardiovascular, metabolic, or musculoskeletal disorders; * Those regularly using anti-inflammatory drugs within the last 4-weeks * Current use of prescription medications that may influence adaptation to exercise (hormone therapies, peptides, etc.) * Current consistent chronic use (within the past 2 weeks) of creatine, rhodiola, L-Theanine, glycerol, or other products which contain any of these ingredients. * Current consistent chronic use (within the past 2 weeks) of stimulants other than caffeine * Current consistent chronic use (within the past 2 weeks) of ingredients that may promote hydration or enhance physical performance. * Allergies to study-related materials * Any condition that may impair their ability to complete the required exercises (determined during screening). * Female subjects must not be pregnant or lactating * Are unable to provide informed consent or are non-English speakers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Applied Science & Performance Institute
Tampa, Florida, 33634, United States
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Other studies related to the condition(s) this trial covers.
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