Can a simple gum-numbing shot before kids' dental surgery cut anesthesia use and help the planet?
NCT ID NCT07608900
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether giving children a local anesthetic injection in the gums before dental surgery under general anesthesia reduces the amount of sevoflurane (the gas used to keep them asleep) needed. Eighty children aged 4 to 12 will be randomly assigned to receive either the numbing shot or no shot before their procedure. The researchers will measure sevoflurane use, recovery time, and the carbon footprint of the anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Articaine with epinephrine (local anesthetic)
- What this could lead to
- If it works, this could show a simple way to reduce the amount of general anesthesia needed for children's dental procedures, potentially speeding recovery and lowering environmental impact.
- What could go wrong
- This is a small, early-stage trial (80 children) that hasn't started yet. The benefit may be small or not clinically meaningful, and results may not apply to other settings or age groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 4 to 12 years * Scheduled for elective day-case dental treatment under general anesthesia * ASA physical status I or II * Planned sevoflurane-based general anesthesia * Planned oral endotracheal intubation * Eligibility for standardized low-flow anesthesia with fresh gas flow of 1 L/min * Eligibility for BIS-guided sevoflurane titration * Written informed consent obtained from a parent or legal guardian Exclusion Criteria: * Age younger than 4 years or older than 12 years * ASA physical status III or higher * Emergency dental procedures * Known allergy or contraindication to sevoflurane * Known allergy or contraindication to amide local anesthetics, articaine, or epinephrine * Known or suspected malignant hyperthermia susceptibility * Significant cardiovascular, respiratory, hepatic, renal, or neurological disease requiring non-standard anesthetic management * Chronic opioid or sedative use * Planned airway management other than oral endotracheal intubation * Dental procedures in which withholding pre-emptive local anesthesia is considered clinically inappropriate for safety or hemostasis * Refusal of participation by parent or legal guardian
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
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