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Study tracks frailty after surgery to predict who lives longer

NCT ID NCT07322809

Knowledge-focused Sponsor: Chinese PLA General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed over 4,400 older surgical patients to see how their frailty levels changed after surgery and whether those changes were linked to dying within one year. Researchers measured frailty before and after surgery and tracked deaths through phone calls. The goal was to better understand frailty patterns and identify factors that might help improve outcomes for older adults after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

4,417 people

The number who actually took part.

Started

Apr 2020

Finished

Apr 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients' frailty was assessed using the FRAIL scale at four time points: preoperatively and at 1, 3, and 6 months postoperatively. Patients were classified into distinct frailty trajectory groups using latent class trajectory modeling. One-year all-cause mortality was ascertained through structured telephone follow-up.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged ≥65 years; * Underwent elective non-cardiac, non-neurosurgical procedures; * Completed standardized frailty assessments both preoperatively and postoperatively. Exclusion Criteria: * Severe dementia, language disorders, significant hearing or visual impairments, or coma; * Cognitive function below the Mini-Mental State Examination (MMSE) thresholds (\<18 for illiterate individuals, \<21 for individuals with primary education, and \<25 for individuals with secondary education or higher); * Surgery performed under local anesthesia or monitored anesthesia care; * Surgical duration ≤30 minutes; * Missing data on postoperative complications or one-year mortality required for this study; * Incomplete frailty assessments at 1, 3, and 6 months after surgery.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

All-cause mortality Frailty in older adults Trajectory

Contacts and locations

Locations

  • 28 Fuxing Road, Haidian District

    Beijin, Beijing Municipality, 100853, China

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