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Can brain zaps restore hand function after stroke?

NCT ID NCT02284087

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two types of non-invasive brain stimulation (called paired associative stimulation) to see if they could help improve hand movement in people who had a stroke. 81 participants (60 stroke survivors and 24 healthy volunteers) took part. The main goal was to understand how the stimulation changes brain activity, not to prove it works as a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

81 people

The number who actually took part.

Started

Jan 2015

Finished

Nov 2018

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Stroke patients

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria FOR PATIENTS: * First event ischemic stroke with hand motor deficit * Time since stroke \> 30 days * Stroke lesion sparing the primary motor cortex (hand knob area) * Age between 18 and 85 ans Exclusion Criteria FOR PATIENTS: * No homonymous hemianopia * No contra-indications for TMS and MRI * Pregnancy * Epilepsia * Any pathology that threatened the 1 month follow up Inclusion Criteria FOR HEALTHY SUBJECTS: * Age between 18 and 85 * Right handed Exclusion Criteria FOR HEALTHY SUBJECTS * No contra-indications for TMS and MRI * Pregnancy * Any cerebral pathology or pathology that threatened the 1 month follow up

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Conditions

The condition(s) this trial relates to.

ischemic stroke movement disorder stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke and healthy subjects

Contacts and locations

Locations

  • ICM, CIC Neurosciences

    Paris, 75013, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.