New therapy aims to stop depression before it starts in At-Risk teens
NCT ID NCT06273137
First seen Apr 03, 2026 · Last updated May 23, 2026 · Updated 8 times
Summary
This study tests a therapy called Positive Affect Therapy (PAT) to see if it can prevent depression in teens aged 12-16 who have experienced two or more adverse childhood events (like abuse or neglect). The therapy focuses on increasing positive feelings and reward sensitivity. Researchers will compare PAT to supportive therapy or a waitlist in 300 teens who are not currently depressed, tracking their mood and inflammation over a year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California Irvine
RECRUITINGIrvine, California, 92617, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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