Pig-Derived gum patch aims to boost dental implant success
NCT ID NCT07436091
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a patch made from pig collagen (Derma OsteoBiol®) to thicken gum tissue around dental implants. Fifteen adults will receive the treatment, and researchers will measure gum thickness changes and track pain and quality of life over one year. The goal is to see if this material improves implant appearance and comfort.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Patients must have the ability to fully understand the nature of the proposed surgery, voluntarily consent to participate and signed the Informed Consent Form before any study related procedures are performed. * Agree with data collection and analyses. * Males or females who are a minimum of 18 years of age or older. * Ability to comply with study-related procedures, including maintaining good oral hygiene and attending follow-up appointments. * Implant placement at least 6 weeks prior to enrolment. * There must be a need for soft tissue augmentation in an implant side. * Implant located in the posterior areas of the maxilla or mandibula (molar or 2nd premolars). * Basic periodontal examination (BPE) score must be less than 2. * patients exhibiting KT width of \>2 mm at the buccal aspect of the implant. Exclusion Criteria: * • Patients who meet any of the following exclusion criteria are not eligible for inclusion in the study. * General contraindications for dental and/or surgical treatment, including the use of anticoagulants. * Presence of a vertical bone dehiscence greater than 3 mm at the implant site, as assessed at the time of soft tissue augmentation surgery. * Heavy smoking habit, defined as consuming more than 10 cigarettes per day. * Presence of active periodontal or peri-implant disease. * Insulin-dependent diabetes. * History of malignancy, radiotherapy, or chemotherapy for malignancy within the past 5 years. * Women of childbearing age who are not using a highly effective method of contraception. * Pregnancy or breastfeeding. * Previous or current use of medication that affects mucosal healing in general, such as steroids or large doses of anti-inflammatory drugs. * Any disease or condition affecting connective tissue metabolism, such as arterial diseases in the operating area, bone metabolic disorders, or alcohol abuse. * Systemic diseases such as diabetes or autoimmune diseases. * Allergy to collagen. * Participation in an investigational device or drug clinical trial within the last 6 months. * Inadequate oral hygiene (FMPS\>25%) * An adverse event occurred, whether or not study device related, which precluded continued treatment;
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculdade De Medicina Dentaria da Universidade do Porto
Porto, 4200-393, Portugal