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Can targeted exercises and nerve stretching restore a symmetrical smile?

NCT ID NCT07758543

Symptom relief Sponsor: Foundation University Islamabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Sep 16, 2026 · Updated 3 times

Summary

This trial asks whether adding gentle nerve mobilization to standard PNF exercises can improve facial symmetry and movement in people with Bell's palsy, a condition causing one-sided facial weakness. Adults aged 15 to 60 with moderate to severe Bell's palsy will be randomly assigned to receive either PNF alone or PNF plus nerve mobilization. Facial function and symmetry are measured at the start and after four weeks using standard grading scales.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A combination of proprioceptive neuromuscular facilitation (PNF) exercises and gentle facial nerve mobilization, added to conventional therapy
What this could lead to
If effective, this combined therapy could offer a better non-drug way to restore facial symmetry and movement in people with Bell's palsy.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. The therapy may not outperform standard PNF alone, and benefits could vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 38 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 15-60 years. * Both male and female. * Patient diagnosed with bells palsy by neurologist or relevant specialist. * Patients with moderate to severe Bell's palsy evaluated by Modified House-Brackman SCALE * Patient without exposure to any other rehabilitation program * Patients within the acute or subacute phases (within 6 months of onset) Exclusion Criteria: * Patients with a history of recurrent Bell's palsy or other neurological disorders (e.g., stroke, multiple sclerosis) * Patients with pacemakers, metal implants or other contraindications for electrical muscle stimulation. * Presence of facial trauma or surgical interventions that might interfere with rehabilitation outcomes. * Co-existing medical conditions (e.g., diabetes mellitus, infections, or malignancies) that might impair nerve recovery or affect study outcomes

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Conditions

The condition(s) this trial relates to.

Bell's palsy Facial Asymmetry facial paralysis hemifacial hypertrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bell's palsy Facial asymmetry Facial paralysis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Foundation University College of Physical Therapy

    RECRUITING

    Islamabad, 44000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.