New pneumonia vaccine shows promise in early trial

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ≥2 years old healthy population; * Subjects and/or guardians or trustees voluntarily signed informed consent forms and could comply with the requirements of the clinical trial protocol; * Had not received any pneumonia vaccine in the last 5 years； * Note: Healthy people do not include the following conditions: ① congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc.; ② History of epilepsy and mental illness; ③ Patients with congenital or acquired immunodeficiency, HIV infection, lymphoma, leukemia, systemic lupus erythematosus (SLE), juvenile rheumatoid arthritis (JRA), or other autoimmune diseases; Have been diagnosed with congenital or acquired immunodeficiency, HIV infection, lymphoma, leukemia, or other autoimmune diseases; ⑤ serious liver and kidney diseases, malignant tumors, all kinds of acute diseases or in the acute phase of chronic disease; Adults have diabetes, severe cardiovascular disease, and high blood pressure (systolic blood pressure ≥140mmHg or diastolic blood pressure ≥90mmHg) that cannot be controlled by medication. Exclusion Criteria: * Armpit temperature \>37.0℃ before inoculation; * Family history of seizures or convulsions, epilepsy, and mental illness; * People with a progressive neurological disorder or a history of Guillain-Barre syndrome; * The patients with clinically significant abnormalities in blood biochemistry and routine blood tests were tested before vaccination； * People who received immunoenhancement or suppressant therapy within 3 months (continuous oral or intravenous infusion for more than 14 days); * History of abnormal coagulation function (such as deficiency of coagulation factor, coagulation disease); * Primary and secondary immunocompromised individuals (thyroid, pancreas, liver, spleen excision history, or need treatment for thyroid disease within the last 12 months); * History of severe allergic reactions to vaccinations; * Allergy to any component of the investigational vaccine; * Have received live attenuated vaccine within 14 days; Other vaccines received within 7 days; * Participating in or planning to participate in other clinical trials; * Women of childbearing age are lactating, pregnant or planning to become pregnant in the near future; * The investigator determined that other conditions were not suitable for participation in the clinical trial.