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Can a simple vaccine boost immunity in CAR T-Cell patients?

NCT ID NCT04745559

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 23 times

Summary

This study looks at whether giving a pneumococcal vaccine (PCV13) before and after CAR T-cell therapy can improve the body's ability to fight off pneumococcus bacteria. It involves 26 adults with certain types of lymphoma who are scheduled for CAR T-cell treatment. The main goal is to see if the vaccine helps create a stronger immune response by day 90 after therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.