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Heart surgery bleeding risk: study reveals transfusion needs for patients on clopidogrel

NCT ID NCT07600060

Knowledge-focused Sponsor: Aga Khan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study reviewed medical records of 227 adults aged 30-80 who had heart bypass surgery while taking the blood thinner clopidogrel. Researchers wanted to see how often these patients needed platelet transfusions and how much they bled after surgery. The goal was to better understand bleeding risks and transfusion needs in this specific group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

227 people

The number who actually took part.

Started

Jul 2022

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All eligible patients admitted to the cardiac intensive care unit (CICU) for open-heart surgery were included.

Ages

30 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * CICU patients who underwent cardiac surgery * Adults aged 30-80 years undergoing cardiac surgery with cardiopulmonary bypass * Patients who received dual antiplatelet therapy, last dose within 5 days before surgery Exclusion Criteria: * BMI \> 40 kg/m² * Repeat open-heart surgery (reoperation) * Transferred open-chest procedures * Active liver disease * Chronic lung disease * Dialysis dependence * Intra-aortic balloon pump (IABP) in place pre- or post-operatively * Major neurological deficit within the past 6 months * Incomplete clinical records

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patients on clopidogrel Platelets transfusion

Contacts and locations

Locations

  • Aga khan University

    Karachi, Sindh, 7480 0, Pakistan