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Heel pain mystery: is the brain making it worse?

NCT ID NCT07640620

Knowledge-focused Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the brain and nervous system (central sensitization) play a role in the pain of plantar fasciitis, a common cause of heel pain. Researchers will measure pain sensitivity, ultrasound images of the foot, and psychological factors in 128 adults with the condition. The goal is to better understand what drives pain in these patients, which could guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand why some people with plantar fasciitis have persistent pain, potentially leading to more targeted treatments.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test any new therapy, and results may not change current care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Individuals applying to the Physical Medicine and Rehabilitation Outpatient Clinic of Sultan 2. Abdülhamid Han Training and Research Hospital will be evaluated, and those who meet the inclusion criteria for the groups and sign the voluntary consent form will be included in the study.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Plantar Fasciitis Group 1. Inclusion criteria * Be between the ages of 18-65 * Have unilateral heel pain that has been ongoing for at least 3 months, particularly worsening with the first few steps in the morning and increasing with weight-bearing activities throughout the day * Have tenderness on palpation of the medial calcaneal tubercle * Have read and signed the volunteer consent form (VCF) 2. Exclusion criteria * Being under 18 years old or over 65 years old * Having a history of physical therapy, injection, radiation, or surgery targeting the plantar fascia within the last 6 months * Calcaneus fracture, tumor, or cyst related to the plantar fascia * Foot deformity (club foot, pes cavus, calcaneovalgus, etc.) * Lumbosacral radiculopathy, tarsal tunnel syndrome, peripheral neuropathy * Rheumatic diseases such as rheumatoid arthritis, ankylosing spondylitis, gout * Foot and ankle osteoarthritis * Presence of osteomyelitis or skin infection in the foot * Systemic diseases such as kidney and liver failure, diabetes, peripheral arterial vascular disease Healthy Control 1. Inclusion criteria * Being completely healthy * Being between the ages of 18 - 65 * Having read and signed the volunteer consent form (BGOF) 2. Exclusion criteria * Being under 18 or over 65 years old * Having any acute or chronic illness * Being illiterate and not giving consent to participate in the study

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Conditions

The condition(s) this trial relates to.

Kinesiophobia plantar fasciitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Plantar fasciitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sultan Abdulhamid Han Training and Research Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

More trials for these conditions

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