Placenta size may warn of pregnancy dangers, study finds
NCT ID NCT07337759
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether the weight and surface area of the placenta can help predict serious pregnancy complications, such as early delivery, low birth weight, or poor newborn health. Researchers examined placentas from 440 women, including those with conditions like high blood pressure or diabetes. They found that smaller-than-expected placentas were linked to worse outcomes for both mother and baby.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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440 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Pregnant women with singleton pregnancies who delivered at the Clinic of Gynecology and Obstetrics, University Clinical Centre of Serbia. The study population includes both healthy pregnant women and women with maternal comorbidities such as hypertensive disorders, diabetes mellitus, and thrombophilia. Placentas were examined after delivery and classified according to placental weight for gestational age.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Pregnant women who delivered at the Clinic of Gynecology and Obstetrics, University Clinical Centre of Serbia * Singleton pregnancy * Available placental examination after delivery * Available clinical and perinatal outcome data * Gestational age at delivery ≥24 weeks Exclusion Criteria: Multiple pregnancy (e.g., twins or higher-order gestations) * Major congenital or chromosomal fetal anomalies * Intrauterine fetal demise * Conditions directly affecting placental weight (e.g., placental mosaicism) * Incomplete clinical, placental, or histopathological data
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinic of Gynecology and Obstetrics, University Clinical Center of Serbia
Belgrade, Serbia