New surgical method aims to curb bleeding and save uteruses in dangerous placenta condition
NCT ID NCT07706062
First seen Jul 15, 2026 · Last updated Jul 28, 2026 · Updated 3 times
Summary
This study looks at a surgical technique called total lower segmentectomy with cervico-corporeal anastomosis (TLS-CCA) combined with mechanical towel compression for women with placenta accreta spectrum (PAS). The goal is to see if this approach can reduce blood loss during delivery and help preserve the uterus. The study includes 30 pregnant women aged 18-45 with a single baby and a prenatal diagnosis of PAS who are planning a scheduled cesarean. Researchers will measure blood loss and blood transfusion needs to assess safety and effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a surgical procedure called total lower segmentectomy with cervico-corporeal anastomosis (TLS-CCA) plus mechanical towel compression
- What this could lead to
- If successful, this technique could offer a safer way to manage placenta accreta, reducing the need for emergency hysterectomy and preserving fertility.
- What could go wrong
- This is a small, early case series with only 30 participants, so results may not apply to all patients. The procedure is complex and carries risks like heavy bleeding or organ injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A consecutive series of pregnant women with an antenatal diagnosis of PAS scheduled for elective, uterus-preserving surgical management via TLS-CCA utilizing the novel towel compression technique
- Ages
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18 to 45 years
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Maternal age 18-45 years * Singleton pregnancy * Antenatal diagnosis of PAS (ultrasound ± MRI) * Planned elective cesarean delivery * Candidate for uterine preservation via TLS-CCA * Provided written informed consent Exclusion Criteria: * Hemodynamic instability necessitating emergency hysterectomy * Placental invasion into adjacent pelvic organs requiring exenteration * Pre-existing severe coagulation disorders * Multiple gestation or major fetal anomalies * Patient refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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How to take part
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The official record
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