Chemotherapy sprayed as a mist inside the abdomen: a new hope for advanced cancer?
NCT ID NCT07487168
First seen Mar 27, 2026 · Last updated Jun 23, 2026 · Updated 13 times
Summary
This early-stage trial tests a technique called PIPAC, which sprays a chemotherapy drug (mitomycin C) as a fine mist directly into the abdomen during a keyhole surgery. It is for 24 people with advanced gastrointestinal cancer that has spread to the lining of the abdomen and cannot be removed by surgery. The main goal is to find the safest dose and see if it can help control the disease and improve quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mitomycin C (chemotherapy drug)
What this could lead to
If successful, this could offer a new palliative treatment option for patients with advanced abdominal cancer who cannot have standard surgery.
What could go wrong
This is a very early Phase 1 trial with only 24 participants, so safety and effectiveness are not yet known. The treatment is for palliative care, not a cure, and may cause side effects from chemotherapy.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.