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Could a brief nerve squeeze improve lung surgery recovery?

NCT ID NCT07259031

Knowledge-focused Sponsor: Ferdane Melike Duran Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether briefly pressing on the phrenic nerve during lung surgery could help reduce complications like air leaks. Researchers compared 55 patients who had this temporary nerve compression with those who did not. They measured diaphragm activity, lung function, and recovery times to see if the technique is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this approach could offer a way to reduce complications like prolonged air leaks after lung surgery.
What could go wrong
This is a small, completed study with only 55 participants, so results may not apply to everyone. The nerve compression is temporary but could still cause unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

55 people

The number who actually took part.

Started

Sep 2019

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (18+) who underwent lobectomy via muscle sparing thoracotomy * Patients with adequate preoperative pulmonary function to tolerate lobectomy * Patients who provided written informed consent for participation. * Patients with available postoperative follow-up data, including EMG and pulmonary function tests Exclusion Criteria: * Patients who underwent wedge resection, segmentectomy, pneumonectomy, or VATS procedures * Patients with previous phrenic nerve injury, diaphragmatic paralysis, or neuromuscular disorders affecting respiratory muscles. * Patients with incomplete postoperative follow-up or missing EMG/PFT data

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Conditions

The condition(s) this trial relates to.

Beckwith-Wiedemann syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMG Phrenic nerve Prolonged air leak

Contacts and locations

Locations

  • Konya City Hospital, Department of Thoracic Surgery

    Konya, Konya, 42080, Turkey (Türkiye)

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