Could light therapy ease Chemo's nerve pain?
NCT ID NCT07681921
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This trial investigates whether photobiomodulation (low-level laser light) can reduce early nerve damage caused by chemotherapy. About 98 cancer patients with early signs of peripheral neuropathy will receive either light therapy or a placebo. The goal is to see if this non-invasive treatment can lessen pain, numbness, and improve daily function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- photobiomodulation (low-level laser light)
- What this could lead to
- If effective, this could offer a non-drug way to ease chemotherapy-induced nerve pain and improve quality of life for cancer patients.
- What could go wrong
- This is a small, early-stage trial. The treatment may not reduce symptoms significantly, and results may not apply to all types of chemotherapy or cancers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 98 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All the patients admitted for medical oncological therapy to the day care facility (Hôpital de Jour) are eligible for the protocol. * Age 18 years or above * Have no documented or observable psychiatric or neurological disorders that might interfere with study participation (e.g., dementia or psychosis) * Be able to understand the ICF and study-related questionnaires * Signed informed consent Exclusion Criteria: * severe or unstable cardio-respiratory or musculoskeletal disease * Peripheral neuropathy previous to chemotherapy * Receiving potentially neurotoxic therapies other than given for cancer treatment * Interruption of more than two consecutive laser treatments
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jules Bordet Institute
Brussels, Brabant, 1070, Belgium
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can an antidepressant calm Chemotherapy's nerve pain?
- Retraining the senses to fight chemotherapy nerve damage
- Retraining the senses to fight chemotherapy nerve damage
- Chilling out Chemo's side effects: could cold therapy shield nerves?
- Essential oils vs. chemo nerve pain: a natural remedy put to the test