New Light-Based scan could spot hidden leg artery disease
NCT ID NCT06579326
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new imaging technique called photoacoustic tomography (PACT) to see blood vessels and oxygen levels in the feet without using dyes or needles. The goal is to help doctors diagnose lower extremity artery disease (LEAD) more accurately and earlier. Researchers will scan 200 people, including those with LEAD and healthy volunteers, to see if PACT adds useful information beyond current tests.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The LEAD patients are diagnosed as LEAD by computed tomography angiography or ultrasound.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Inclusion of the case group 1) LEAD patients; 2) Patients voluntarily take part in the study and write informed consent. 2. Inclusion of the control group 1) Patients without LEAD by ultrasound and clinical diagnosis; 2) Patients voluntarily take part in the study and write informed consent. Exclusion Criteria: 1. age \<18 years; 2. pregnant women, nursing mothers and pregnant women in preparation; 3. with laser operation contraindication (for example, received a photodynamic therapy in the last month); 4. with metal implants in lower legs or feet; 5. with a history of mental illnesses or abuse of drug and alcohol; 7\) with blood phobia or pathological hypotension; 8) with cerebral hemorrhage or peripheral vascular bleeding risk, or history of stroke; 9) with wounds in lower legs or feet; 10) unable or uncooperative with the experimenter.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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the Third Affiliated Hospital of Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510630, China
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