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New hope for pancreatic cancer: targeted drug combo enters human trials

NCT ID NCT07377045

First seen Feb 01, 2026 · Last updated Jun 18, 2026 · Updated 23 times

Summary

This early-stage trial tests a new targeted drug (OMTX705) combined with standard chemotherapy and an immunotherapy for people with advanced pancreatic cancer that has spread. The study has two parts: first, finding the safest dose of OMTX705, then comparing the new combo against standard treatment alone. About 69 adults with metastatic pancreatic cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center (BIDMC)

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinica Universidad de Navarra (CUN)

    RECRUITING

    Pamplona, 31008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clínico Universitario de Santiago - CHUS

    NOT_YET_RECRUITING

    Santiago de Compostela, 15706, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario 12 Octubre

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Donostia

    NOT_YET_RECRUITING

    Donostia / San Sebastian, 20014, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Vall d'Hebron (VHIO)

    NOT_YET_RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ICO- Hospitalet Catalan Institute of Oncology

    RECRUITING

    L'Hospitalet de Llobregat, 08908, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

pancreatic adenocarcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.