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Pharmacists on the frontline: new study aims to cut opioid overdose deaths after prison

NCT ID NCT05776823

Disease control Sponsor: University of Arkansas Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a pharmacist-led program could help people leaving jail get treatment for opioid use disorder and prevent overdoses. Participants received overdose training, Narcan nasal spray, counseling, and referrals to medication treatment after release. The goal was to see if this approach improves treatment access and reduces racial differences in overdose rates.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

267 people

The number who actually took part.

Started

May 2023

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria Narcan Training: * a Re-Entry program participant 7-14 days from release from carceral setting * provide collateral contact information for ≥2 persons (to ensure consistent contact/follow up) * have a reliable landline or mobile phone to be contacted by pharmacist * plan to remain in the Little Rock area for at least 6 months * able to read and write English * able to provide informed consent * possesses manual dexterity; physical ability to roll a person onto her/his/their back and side * have no allergy to naloxone hydrochloride (active ingredient in Narcan nasal spray)- * identified on the RODS screener as positive for OUD. BIRT/SMC: * a Re-Entry program participant 7-14 days from release from the carceral setting * provide contact information for ≥2 persons (to ensure consistent contact/follow -up) * have a reliable landline or mobile phone to be contacted by pharmacist * plan to remain in the Little Rock area for at least 6 months * able to read and write English; able to provide informed consent * identified with OUD. Exclusion Criteria: Narcan training: * not a RE-entry program participant * identified substance use disorders other than OUD BIRT/SMC: * not a RE-entry program participant * identified substance use disorders other than OUD

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Conditions

The condition(s) this trial relates to.

Drug Overdose Harm Reduction opiate dependence poisoning acute opioid poisoning prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use disorder Overdose

Contacts and locations

Locations

  • Pulaski County Regional Detention Center

    Little Rock, Arkansas, 72204, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.