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New eye drop aims to soothe dry eyes from too much screen time

NCT ID NCT07679685

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study compares a new eye drop (perfluorohexyloctane) with a standard one (sodium hyaluronate) for people whose eyes get dry from using screens for more than 6 hours a day. Participants aged 18 to 70 with mild to moderate dry eye will use the drops four times daily for 8 weeks. The main goal is to see if the new drop improves tear film stability better than the standard treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
perfluorohexyloctane eye drops
What this could lead to
If effective, this could offer a new option for people whose eyes feel dry and irritated from long hours on computers or phones.
What could go wrong
This is a Phase 4 trial with 159 participants, so results may not apply to everyone. The new drops might not work better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 159 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-70 years (inclusive), male or female; 2. Subject reports dry eye symptoms for at least 6 months; 3. Diagnosis of mild to moderate dry eye according to the Chinese Dry Eye Expert Consensus (2020) criteria: * Mild dry eye: fluorescein tear film break-up time (FBUT) ≥2 seconds, no significant ocular surface damage signs, corneal fluorescein staining score \<5; * Moderate dry eye: FBUT ≥2 seconds AND corneal fluorescein staining dots \<30 or not exceeding 2 quadrants; 4. Normal tear secretion: Schirmer I test ≥10 mm/5 min; 5. Daily electronic screen usage \>6 hours; 6. Electronic screen use for at least 5 days/week, for more than 1 year; 7. Understands and provides written informed consent. Exclusion Criteria: 1. Allergy or hypersensitivity to any component of the study drugs; 2. Requires the use of artificial tears (other than study drug), secretagogues, ocular surface repair agents, anti-inflammatory/antibiotic eye drops, or other dry eye-related drugs (e.g., muscarinic receptor blockers for visual fatigue) during the study period; 3. Presence of any of the following ocular or systemic conditions: * Active ocular infection, ocular inflammation, or active ocular allergy; * Conjunctivochalasis, nasolacrimal duct obstruction; * Glaucoma or elevated intraocular pressure; * Retinal disease or ocular tumor; * Requirement to wear contact lenses during the study; * Obstructive sleep apnea syndrome or sleep disorders; * Planned or ongoing physical therapy (intense pulsed light, meibomian gland massage, warm compress, thermopulsation) within 2 weeks before enrollment through the end of study; 4. Ocular surgery within 3 months prior to enrollment, incomplete recovery from previous ocular surgery, or planned ophthalmic surgery during the study period; 5. Current smoker; 6. Pregnant or breastfeeding women, or women planning to become pregnant during the study period; 7. Uncontrolled systemic disease, or use of systemic medications (e.g., beta-blockers, benzodiazepines, corticosteroids, antihistamines, or other medications that may interfere with tear production); 8. History of anxiety or depression; 9. Any other condition that, in the judgment of the investigator, would make the subject unsuitable for participation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    9 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Aier-Intech Eye Hospital

    Beijing, China

  • Beijing Anzhen Hospital

    Beijing, Beijing Municipality, China

  • Chinese PLA General Hospital

    Beijing, China

  • Eye & ENT Hospital of Fudan University

    Shanghai, China

  • Guangdong Provincial People's Hospital

    Guangzhou, China

  • Peking Union Medical College Hospital

    Beijing, China

  • Sun Yat-sen Memorial Hospital

    Guangzhou, China

  • Xi'an Fourth Hospital

    Xi'an, China

  • Zhongshan City People's Hospital

    Zhongshan, China

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