New eye drop aims to soothe dry eyes from too much screen time
NCT ID NCT07679685
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study compares a new eye drop (perfluorohexyloctane) with a standard one (sodium hyaluronate) for people whose eyes get dry from using screens for more than 6 hours a day. Participants aged 18 to 70 with mild to moderate dry eye will use the drops four times daily for 8 weeks. The main goal is to see if the new drop improves tear film stability better than the standard treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- perfluorohexyloctane eye drops
- What this could lead to
- If effective, this could offer a new option for people whose eyes feel dry and irritated from long hours on computers or phones.
- What could go wrong
- This is a Phase 4 trial with 159 participants, so results may not apply to everyone. The new drops might not work better than existing treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 159 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18-70 years (inclusive), male or female; 2. Subject reports dry eye symptoms for at least 6 months; 3. Diagnosis of mild to moderate dry eye according to the Chinese Dry Eye Expert Consensus (2020) criteria: * Mild dry eye: fluorescein tear film break-up time (FBUT) ≥2 seconds, no significant ocular surface damage signs, corneal fluorescein staining score \<5; * Moderate dry eye: FBUT ≥2 seconds AND corneal fluorescein staining dots \<30 or not exceeding 2 quadrants; 4. Normal tear secretion: Schirmer I test ≥10 mm/5 min; 5. Daily electronic screen usage \>6 hours; 6. Electronic screen use for at least 5 days/week, for more than 1 year; 7. Understands and provides written informed consent. Exclusion Criteria: 1. Allergy or hypersensitivity to any component of the study drugs; 2. Requires the use of artificial tears (other than study drug), secretagogues, ocular surface repair agents, anti-inflammatory/antibiotic eye drops, or other dry eye-related drugs (e.g., muscarinic receptor blockers for visual fatigue) during the study period; 3. Presence of any of the following ocular or systemic conditions: * Active ocular infection, ocular inflammation, or active ocular allergy; * Conjunctivochalasis, nasolacrimal duct obstruction; * Glaucoma or elevated intraocular pressure; * Retinal disease or ocular tumor; * Requirement to wear contact lenses during the study; * Obstructive sleep apnea syndrome or sleep disorders; * Planned or ongoing physical therapy (intense pulsed light, meibomian gland massage, warm compress, thermopulsation) within 2 weeks before enrollment through the end of study; 4. Ocular surgery within 3 months prior to enrollment, incomplete recovery from previous ocular surgery, or planned ophthalmic surgery during the study period; 5. Current smoker; 6. Pregnant or breastfeeding women, or women planning to become pregnant during the study period; 7. Uncontrolled systemic disease, or use of systemic medications (e.g., beta-blockers, benzodiazepines, corticosteroids, antihistamines, or other medications that may interfere with tear production); 8. History of anxiety or depression; 9. Any other condition that, in the judgment of the investigator, would make the subject unsuitable for participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
9 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Aier-Intech Eye Hospital
Beijing, China
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Beijing Anzhen Hospital
Beijing, Beijing Municipality, China
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Chinese PLA General Hospital
Beijing, China
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Eye & ENT Hospital of Fudan University
Shanghai, China
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Guangdong Provincial People's Hospital
Guangzhou, China
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Peking Union Medical College Hospital
Beijing, China
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Sun Yat-sen Memorial Hospital
Guangzhou, China
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Xi'an Fourth Hospital
Xi'an, China
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Zhongshan City People's Hospital
Zhongshan, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a 13-Minute eye exercise routine ease screen strain?
- Gel plug in tear duct tested to keep eyes moist after cataract surgery
- A gel plug for tear ducts may stop post-surgery dry eye
- Can a thymosin beta 4 eye drop soothe dry eye?
- Insulin-spiked eye drops may ease stubborn dry eye in Sjögren's patients
- Can four eye scanners detect how miebo stabilizes tears?