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New cancer drug trial halted early after testing on 10 patients

NCT ID NCT06546553

First seen Nov 06, 2025 · Last updated Jun 18, 2026 · Updated 35 times

Summary

This early-phase study tested a new drug (PF-07826390) alone or with another drug (sasanlimab) in people with advanced solid tumors like lung, colon, kidney, and ovarian cancers. The goal was to check safety, find the right dose, and see if the drug shrinks tumors. Only 10 people took part before the study was stopped early.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beverly Hills Cancer Center

    Beverly Hills, California, 90211, United States

  • Florida Cancer Specialists

    Orlando, Florida, 32827, United States

  • Florida Cancer Specialists & Research Institute, LLC

    Fort Myers, Florida, 33916, United States

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    West Valley City, Utah, 84119, United States

  • START San Antonio

    San Antonio, Texas, 78229, United States

  • Sarah Cannon Research Institute at Florida Cancer Specialists

    Orlando, Florida, 32827, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

Conditions

The condition(s) this trial relates to.

colorectal carcinoma colorectal neoplasm head and neck squamous cell carcinoma kidney cancer melanoma neoplasm Neoplasm Metastasis non-small cell lung carcinoma ovarian cancer ovarian carcinoma rectal disorder renal cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.