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Whooping cough booster study shows strong immune response in south african kids

NCT ID NCT04300192

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 24 times

Summary

This study tested a Tdap-IPV booster vaccine in 273 children in South Africa to see how their immune systems responded based on the whooping cough vaccine they received as infants. Researchers measured antibody levels and cell-mediated immunity over time. The goal was to understand if the type of vaccine given in early childhood affects the booster's effectiveness.

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Contacts and locations

Locations

  • Investigational Site Number : 7100001

    Cape Town, 7925, South Africa

  • Investigational Site Number : 7100002

    Middelburg, 1055, South Africa

  • Investigational Site Number : 7100003

    Johannesburg, 1619, South Africa

Conditions

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