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New personalized vaccine aims to fight advanced colon and pancreatic cancers

NCT ID NCT07587827

First seen Jun 01, 2026 · Last updated Jun 19, 2026 · Updated 4 times

Summary

This early-phase trial tests a personalized cancer vaccine called ODI-2001 in 77 people with advanced colon or pancreatic cancer. The vaccine is custom-made for each patient and combined with an immune-boosting drug (ipilimumab). The goal is to find the safest dose and see if it can slow cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU Jean Minjoz

    Besançon, 25000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Georges-François Leclerc

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Personalized cancer vaccine (DNA neoantigen vaccine + MVA viral vector + ipilimumab)

What this could lead to

If successful, this could point toward a new personalized immunotherapy option for advanced colon or pancreatic cancers.

What could go wrong

This is a very early Phase 1 trial with only 77 participants, so it may not show clear benefit. The vaccine includes ipilimumab, which can cause serious immune-related side effects.

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal carcinoma colorectal neoplasm exocrine pancreatic carcinoma malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.