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New drug duo aims to shrink head and neck tumors before surgery

NCT ID NCT07586124

First seen May 20, 2026 · Last updated May 23, 2026 · Updated 1 time

Summary

This study tests whether adding two drugs (pucotenlimab and becotatug vedotin) to standard surgery can improve outcomes for people with advanced head and neck cancer that can be removed. About 80 participants will receive the drug combination or a placebo before and after surgery. The main goal is to see how many tumors shrink significantly or disappear completely after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital of Shantou University Medical College

    Shantou, Guangdong, 515041, China

    Contact

  • Guangxi Medical University Cancer Hospital

    Nanning, Guangxi, 530021, China

    Contact

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

    Contact

  • Hunan Cancer Hospital

    Changsha, Hunan, 410013, China

    Contact

  • Liaoning Cancer Hospital & institute

    Shenyang, Liaoning, 110042, China

    Contact

  • Ningbo Medical Center Lihuili Hospital

    Ningbo, Zhejiang, 315040, China

    Contact

  • Peking University Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

    Contact

  • Shanghai East Hospital

    Shanghai, Shanghai Municipality, 200120, China

    Contact

  • Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200011, China

    Contact

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510120, China

    Contact

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

    Contact

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, 350005, China

    Contact

  • The Fourth Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 050011, China

    Contact

  • Xiangya Hospital of Central South University

    Changsha, Hunan, 410008, China

    Contact

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

    Contact

Conditions

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