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Gum treatment may lower whole-body stress, study suggests

NCT ID NCT06978712

First seen May 28, 2026 · Last updated Jun 20, 2026 · Updated 7 times

Summary

This study looks at whether a deep cleaning procedure called sub-gingival instrumentation can reduce allostatic load—the wear and tear on the body from chronic stress—in people with gum disease. Researchers will measure inflammation, blood sugar, and cholesterol levels in 112 adults aged 30-50. The goal is to see if treating gum disease has benefits beyond the mouth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • PGIDS

    RECRUITING

    Rohtak, Haryana, 124001, India

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sub-gingival instrumentation (deep cleaning of gums)

What this could lead to

If successful, this could show that treating gum disease helps lower the body's overall stress load, pointing to broader health benefits beyond the mouth.

What could go wrong

This is a small, early-stage study without a control group, so results may not be definitive. The effect on stress markers may be small or not last long.

Conditions

The condition(s) this trial relates to.

chronic periodontitis Inflammation periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.