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Scientists probe the inner workings of a needle treatment for back pain
NCT ID NCT07524010
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a procedure called percutaneous electrolysis affects the body on a biochemical level in people with low back pain. Researchers will take blood samples before and after the treatment to see which proteins and fats change. The goal is to understand why this technique might help relieve pain, not to test if it works as a treatment. Only 20 physically active men aged 18 to 48 are taking part.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- percutaneous electrolysis (a procedure using a fine needle and low-intensity electrical current)
- What this could lead to
- If successful, this study could reveal how percutaneous electrolysis works on a molecular level, potentially leading to better treatments for low back pain.
- What could go wrong
- This is a very small, early-stage study with only 20 participants, so results may not apply to everyone. It focuses on biological markers, not on whether the treatment actually reduces pain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- 1. Male participants aged 18 to 48 years. 2. Presence of low back pain at the time of enrollment. 3. Identification of the lumbar multifidus muscle as a target for the intervention. 4\. Good general health status, as determined by medical history. 5. Physically active or athletic individuals. 6. Non-smokers. 7. Ability and willingness to comply with study procedures. 8. Provision of written informed consent prior to participation. Exclusion Criteria: * 1\. History of spinal surgery or significant spinal trauma. 2. Presence of neurological disorders affecting the lumbar spine or lower limbs. 3\. Known systemic inflammatory, metabolic, or autoimmune diseases. 4. Use of anti-inflammatory, analgesic, or corticosteroid medication within a predefined period prior to enrollment. 5\. Coagulation disorders or current use of anticoagulant therapy. 6. Active infection, skin lesion, or dermatological condition at the intervention site. 7\. Contraindications to invasive physiotherapy or needle-based procedures. 8. Participation in another interventional clinical study within the previous months. 9\. Inability to tolerate blood sampling procedures.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Piamonte University
Vercelli, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Radiofrequency device tested as Add-On for stubborn back pain
- Back muscles hold clues for treating recurrent low back pain
- Skip the GP? physiotherapy first for back pain put to the test
- Can yoga ease back pain when recovery looks unlikely?
- Can a second injection target the source of stubborn back pain?
- Can releasing a deep back muscle ease pain and help you breathe better?