New drug may help restore blood flow in critically ill children
NCT ID NCT07519226
First seen Apr 21, 2026 · Last updated May 21, 2026 · Updated 5 times
Summary
This study tested whether penehyclidine hydrochloride, a drug that blocks certain nerve signals, can improve tiny blood vessel function in children with shock better than the standard drug atropine. The trial included 98 children aged 28 days to 18 years who still had signs of poor blood flow even after their blood pressure was stabilized. The main goal was to see how quickly the drug could normalize capillary refill time, a simple measure of blood circulation.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Guangzhou Women and Children's Medical Center
Guangzhou, Guangdong, 510000, China
Conditions
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