New combo therapy aims to outsmart resistant head and neck cancer
NCT ID NCT06589804
First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 21 times
Summary
This study tests whether adding cetuximab to standard immunotherapy (pembrolizumab) helps people with advanced head and neck cancer that has stopped responding to platinum chemotherapy live longer. About 158 adults with cancer that has returned or spread will receive either pembrolizumab alone or both drugs together. The goal is to see if the combination shrinks tumors and improves survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 158 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Nov 2029
An estimate. End dates often move.
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Histologically confirmed diagnosis head and neck squamous cell carcinomas (HNSCC). * Previously untreated for recurrent and/or metastatic disease incurable by local therapies. * Primary tumor location of oral cavity, oropharynx, larynx, or hypopharynx. * Note: Other primary tumor sites of HNSCC, including nasopharynx primary tumor are not eligible. Unknown primary tumors may be eligible and can be enrolled at the discretion of the treatment team with approval by the study chair. * Measurable disease. * Must have platinum-refractory disease defined as disease progression during or ≤ 29 weeks after completion of definitive therapy (chemoradiation therapy) or adjuvant (post-operative) therapy. * Patient must have a combined positive score PD-L1 positive (CPS \>/= 1) tumor. * Any radiation therapy must be completed \>= 10 days prior to registration. * Patients should not have received any prior treatment in the recurrent or metastatic setting. * Prior therapy with neoadjuvant or induction anti PD-1/PD-L1 monoclonal antibody or cetuximab in the curative setting is allowed if last treatment dose was \>= 26 weeks prior to registration without evidence of disease progression during that treatment period. * Patient has not received a live vaccine within 30 days prior to registration. * Patient does not have a history of any contraindication or has a severe hypersensitivity to any component of pembrolizumab or cetuximab (≥ grade 3). * Patient has not received chronic systemic steroid therapy (in dosing exceeding 10 mg daily of prednisone or equivalent) or any other form of immunosuppressive therapy within 7 days prior to registration. * Patient with oropharyngeal cancer only must have negative results from testing of human papillomavirus (HPV) status defined as p16 immunohistochemistry (IHC) and/or HPV in situ hybridization (ISH). * Note: A Clinical Laboratory Improvement Act (CLIA) certified circulating tumor HPV deoxyribonucleic acid (ctHPVDNA) assay can be used if tissue sample is not available. * Age ≥ 18 years. * Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2. * Absolute neutrophil count (ANC) ≥ 1,500/mm\^3. * Platelet count ≥ 100,000/mm\^3. * Hemoglobin (Hgb) ≥ 9 g/dL (if \< 9 g/dL, then transfusions are acceptable to increase hemoglobin above 9 g/dL). * Creatinine ≤ 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance ≥ 30 mL/min using the Cockcroft-Gault formula for participant with creatinine levels \> 1.5 x institutional ULN. * Total bilirubin ≤ 1.5 x ULN OR direct bilirubin \< ULN for participant with total bilirubin \> 1.5 x institutional ULN. * Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamic-pyruvic transaminase \[SGPT\]) ≤ 3.0 x ULN unless liver metastases are present in which case \< 5.0 x ULN. * Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic, and teratogenic effects. * Therefore, for women of childbearing potential only, a negative pregnancy test done ≤ 7 days prior to registration is required. * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen should be included. * For treated/stable brain metastases: Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression. * Patients with new or progressive brain metastases (active brain metastases) or leptomeningeal disease are eligible if the treating physician determines that immediate CNS specific treatment is not required and is unlikely to be required during the first cycle of therapy. * HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months prior to registration are eligible for this trial. * For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated. * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load. * Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better. * Patients does not have a history of active myocarditis. * Patients does not have a history of any form of pneumonitis or diffuse idiopathic or immune mediated interstitial pulmonary disease. * Patient does not have a history of solid organ transplantation.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Metastatic head and neck squamous cell carcinoma are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
194 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
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AMG Crystal Lake - Oncology
RECRUITINGCrystal Lake, Illinois, 60014, United States
Contact Email: •••••@•••••
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AMG Libertyville - Oncology
RECRUITINGLibertyville, Illinois, 60048, United States
Contact Email: •••••@•••••
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Abbott-Northwestern Hospital
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Advocate Christ Medical Center
RECRUITINGOak Lawn, Illinois, 60453-2699, United States
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Advocate Good Samaritan Hospital
RECRUITINGDowners Grove, Illinois, 60515, United States
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Advocate Good Shepherd Hospital
RECRUITINGBarrington, Illinois, 60010, United States
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Advocate High Tech Medical Park
RECRUITINGPalos Heights, Illinois, 60463, United States
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Advocate Illinois Masonic Medical Center
RECRUITINGChicago, Illinois, 60657, United States
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Advocate Lutheran General Hospital
RECRUITINGPark Ridge, Illinois, 60068, United States
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Advocate Outpatient Center - Oak Lawn
RECRUITINGOak Lawn, Illinois, 60453, United States
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Advocate Sherman Hospital
RECRUITINGElgin, Illinois, 60123, United States
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Advocate South Suburban Hospital
RECRUITINGHazel Crest, Illinois, 60429, United States
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Atrium Medical Center-Middletown Regional Hospital
RECRUITINGFranklin, Ohio, 45005-1066, United States
Contact Email: •••••@•••••
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Aurora Bay Area Medical Group-Marinette
RECRUITINGMarinette, Wisconsin, 54143, United States
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Aurora BayCare Medical Center
RECRUITINGGreen Bay, Wisconsin, 54311, United States
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Aurora Cancer Care-Grafton
RECRUITINGGrafton, Wisconsin, 53024, United States
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Aurora Cancer Care-Kenosha South
RECRUITINGKenosha, Wisconsin, 53142, United States
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Aurora Cancer Care-Milwaukee
RECRUITINGMilwaukee, Wisconsin, 53209, United States
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Aurora Cancer Care-Milwaukee West
RECRUITINGWauwatosa, Wisconsin, 53226, United States
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Aurora Cancer Care-Racine
RECRUITINGRacine, Wisconsin, 53406, United States
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Aurora Cancer Care-Southern Lakes VLCC
RECRUITINGBurlington, Wisconsin, 53105, United States
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Aurora Health Care Germantown Health Center
RECRUITINGGermantown, Wisconsin, 53022, United States
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Aurora Medical Center in Summit
RECRUITINGSummit, Wisconsin, 53066, United States
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Aurora Saint Luke's Medical Center
RECRUITINGMilwaukee, Wisconsin, 53215, United States
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Aurora Saint Luke's South Shore
RECRUITINGCudahy, Wisconsin, 53110, United States
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Aurora Sinai Medical Center
RECRUITINGMilwaukee, Wisconsin, 53233, United States
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Aurora West Allis Medical Center
RECRUITINGWest Allis, Wisconsin, 53227, United States
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Avera Cancer Institute
RECRUITINGSioux Falls, South Dakota, 57105, United States
Contact Email: •••••@•••••
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Avera Cancer Institute - Mitchell
RECRUITINGMitchell, South Dakota, 57301, United States
Contact Email: •••••@•••••
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Avera Cancer Institute at Pierre
RECRUITINGPierre, South Dakota, 57501, United States
Contact Email: •••••@•••••
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Avera Cancer Institute at Yankton
RECRUITINGYankton, South Dakota, 57078, United States
Contact Email: •••••@•••••
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Benefis Sletten Cancer Institute
RECRUITINGGreat Falls, Montana, 59405, United States
Contact Email: •••••@•••••
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Billings Clinic Cancer Center
RECRUITINGBillings, Montana, 59101, United States
Contact Email: •••••@•••••
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Boston Medical Center
RECRUITINGBoston, Massachusetts, 02118, United States
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Bozeman Health Deaconess Hospital
RECRUITINGBozeman, Montana, 59715, United States
Contact Email: •••••@•••••
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Cancer Care Center of O'Fallon
RECRUITINGO'Fallon, Illinois, 62269, United States
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Cancer Care Specialists of Illinois - Decatur
RECRUITINGDecatur, Illinois, 62526, United States
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Cancer Care and Hematology-Fort Collins
RECRUITINGFort Collins, Colorado, 80528, United States
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Cancer Centers of Southwest Oklahoma Research
RECRUITINGLawton, Oklahoma, 73505, United States
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Cancer Hematology Centers - Flint
RECRUITINGFlint, Michigan, 48503, United States
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Carle BroMenn Medical Center
RECRUITINGNormal, Illinois, 61761, United States
Contact Email: •••••@•••••
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Carle Cancer Center
RECRUITINGUrbana, Illinois, 61801, United States
Contact Email: •••••@•••••
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Carle Cancer Institute Normal
RECRUITINGNormal, Illinois, 61761, United States
Contact Email: •••••@•••••
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Carle Physician Group-Effingham
RECRUITINGEffingham, Illinois, 62401, United States
Contact Email: •••••@•••••
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Carle Physician Group-Mattoon/Charleston
RECRUITINGMattoon, Illinois, 61938, United States
Contact Email: •••••@•••••
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Carle at The Riverfront
RECRUITINGDanville, Illinois, 61832, United States
Contact Email: •••••@•••••
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Carlisle Regional Cancer Center
RECRUITINGCarlisle, Pennsylvania, 17015, United States
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Community Hospital of Anaconda
RECRUITINGAnaconda, Montana, 59711, United States
Contact Email: •••••@•••••
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Community Medical Center
RECRUITINGMissoula, Montana, 59804, United States
Contact Email: •••••@•••••
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Condell Memorial Hospital
RECRUITINGLibertyville, Illinois, 60048, United States
Contact Email: •••••@•••••
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Crossroads Cancer Center
RECRUITINGEffingham, Illinois, 62401, United States
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Dartmouth Cancer Center - North
RECRUITINGSaint Johnsbury, Vermont, 05819, United States
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Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
RECRUITINGLebanon, New Hampshire, 03756, United States
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Decatur Memorial Hospital
RECRUITINGDecatur, Illinois, 62526, United States
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Fairview Southdale Hospital
RECRUITINGEdina, Minnesota, 55435, United States
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FirstHealth of the Carolinas-Moore Regional Hospital
RECRUITINGPinehurst, North Carolina, 28374, United States
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Fremont - Rideout Cancer Center
TERMINATEDMarysville, California, 95901, United States
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Genesee Hematology Oncology PC
SUSPENDEDFlint, Michigan, 48503, United States
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Genesys Hurley Cancer Institute
RECRUITINGFlint, Michigan, 48503, United States
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Glens Falls Hospital
ACTIVE_NOT_RECRUITINGGlens Falls, New York, 12801, United States
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Gundersen Lutheran Medical Center
RECRUITINGLa Crosse, Wisconsin, 54601, United States
Contact Email: •••••@•••••
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HaysMed
RECRUITINGHays, Kansas, 67601, United States
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Hennepin County Medical Center
RECRUITINGMinneapolis, Minnesota, 55415, United States
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Hurley Medical Center
RECRUITINGFlint, Michigan, 48503, United States
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IRMC Cancer Center
RECRUITINGIndiana, Pennsylvania, 15701, United States
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Illinois CancerCare-Macomb
RECRUITINGMacomb, Illinois, 61455, United States
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Illinois CancerCare-Peoria
RECRUITINGPeoria, Illinois, 61615, United States
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Jefferson Cherry Hill Hospital
ACTIVE_NOT_RECRUITINGCherry Hill, New Jersey, 08002, United States
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Jefferson Torresdale Hospital
ACTIVE_NOT_RECRUITINGPhiladelphia, Pennsylvania, 19114, United States
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Kootenai Clinic Cancer Services - Post Falls
RECRUITINGPost Falls, Idaho, 83854, United States
Contact Email: •••••@•••••
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Kootenai Clinic Cancer Services - Sandpoint
RECRUITINGSandpoint, Idaho, 83864, United States
Contact Email: •••••@•••••
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Kootenai Health - Coeur d'Alene
RECRUITINGCoeur d'Alene, Idaho, 83814, United States
Contact Email: •••••@•••••
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Lake Regional Hospital
RECRUITINGOsage Beach, Missouri, 65065, United States
Contact Email: •••••@•••••
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Lawrence Memorial Hospital
RECRUITINGLawrence, Kansas, 66044, United States
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Lehigh Valley Hospital - Muhlenberg
RECRUITINGBethlehem, Pennsylvania, 18017, United States
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Lehigh Valley Hospital-Cedar Crest
RECRUITINGAllentown, Pennsylvania, 18103, United States
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Liberty Hospital
RECRUITINGLiberty, Missouri, 64068, United States
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Logan Health Medical Center
RECRUITINGKalispell, Montana, 59901, United States
Contact Email: •••••@•••••
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Lutheran Hospital - Cancer Centers of Colorado
RECRUITINGGolden, Colorado, 80401, United States
Contact Email: •••••@•••••
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Margaret R Pardee Memorial Hospital
RECRUITINGHendersonville, North Carolina, 28791, United States
Contact Email: •••••@•••••
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Marshfield Medical Center - Weston
RECRUITINGWeston, Wisconsin, 54476, United States
Contact Email: •••••@•••••
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Marshfield Medical Center-EC Cancer Center
RECRUITINGEau Claire, Wisconsin, 54701, United States
Contact Email: •••••@•••••
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Marshfield Medical Center-Marshfield
RECRUITINGMarshfield, Wisconsin, 54449, United States
Contact Email: •••••@•••••
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Marshfield Medical Center-River Region at Stevens Point
RECRUITINGStevens Point, Wisconsin, 54482, United States
Contact Email: •••••@•••••
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Mary Greeley Medical Center
RECRUITINGAmes, Iowa, 50010, United States
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McFarland Clinic - Ames
RECRUITINGAmes, Iowa, 50010, United States
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McFarland Clinic - Boone
SUSPENDEDBoone, Iowa, 50036, United States
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McFarland Clinic - Jefferson
SUSPENDEDJefferson, Iowa, 50129, United States
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McFarland Clinic - Marshalltown
RECRUITINGMarshalltown, Iowa, 50158, United States
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McFarland Clinic - Trinity Cancer Center
RECRUITINGFort Dodge, Iowa, 50501, United States
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Medical Center of the Rockies
RECRUITINGLoveland, Colorado, 80538, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Memorial Hospital East
RECRUITINGShiloh, Illinois, 62269, United States
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Memorial Hospital North
RECRUITINGColorado Springs, Colorado, 80920, United States
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Memorial Sloan Kettering Basking Ridge
RECRUITINGBasking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen
RECRUITINGMontvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Memorial Sloan Kettering Commack
RECRUITINGCommack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
RECRUITINGMiddletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau
RECRUITINGUniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester
RECRUITINGHarrison, New York, 10604, United States
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Mercy Hospital
RECRUITINGCedar Rapids, Iowa, 52403, United States
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Mercy Hospital
RECRUITINGCoon Rapids, Minnesota, 55433, United States
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Mercy Hospital South
RECRUITINGSt Louis, Missouri, 63128, United States
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Miami Valley Cancer Care and Infusion
RECRUITINGGreenville, Ohio, 45331, United States
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Miami Valley Hospital
RECRUITINGDayton, Ohio, 45409, United States
Contact Email: •••••@•••••
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Miami Valley Hospital North
RECRUITINGDayton, Ohio, 45415, United States
Contact Email: •••••@•••••
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Miami Valley Hospital South
RECRUITINGCenterville, Ohio, 45459, United States
Contact Email: •••••@•••••
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Minnesota Oncology - Burnsville
RECRUITINGBurnsville, Minnesota, 55337, United States
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Mount Sinai Medical Center
RECRUITINGMiami Beach, Florida, 33140, United States
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Oncology Associates at Mercy Medical Center
RECRUITINGCedar Rapids, Iowa, 52403, United States
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Park Nicollet Clinic - Saint Louis Park
RECRUITINGSaint Louis Park, Minnesota, 55416, United States
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Pocono Medical Center
RECRUITINGEast Stroudsburg, Pennsylvania, 18301, United States
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Poudre Valley Hospital
RECRUITINGFort Collins, Colorado, 80524, United States
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ProHealth D N Greenwald Center
RECRUITINGMukwonago, Wisconsin, 53149, United States
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ProHealth Oconomowoc Memorial Hospital
RECRUITINGOconomowoc, Wisconsin, 53066, United States
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ProHealth Waukesha Memorial Hospital
RECRUITINGWaukesha, Wisconsin, 53188, United States
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ProMedica Flower Hospital
RECRUITINGSylvania, Ohio, 43560, United States
Contact Email: •••••@•••••
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Providence Portland Medical Center
RECRUITINGPortland, Oregon, 97213, United States
Contact Email: •••••@•••••
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Providence Saint Vincent Medical Center
RECRUITINGPortland, Oregon, 97225, United States
Contact Email: •••••@•••••
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Providence Willamette Falls Medical Center
RECRUITINGOregon City, Oregon, 97045, United States
Contact Email: •••••@•••••
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Regions Hospital
RECRUITINGSaint Paul, Minnesota, 55101, United States
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SUNY Upstate Medical Center-Community Campus
RECRUITINGSyracuse, New York, 13215, United States
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Saint Alphonsus Cancer Care Center-Boise
RECRUITINGBoise, Idaho, 83706, United States
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Saint Alphonsus Cancer Care Center-Caldwell
RECRUITINGCaldwell, Idaho, 83605, United States
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Saint Alphonsus Cancer Care Center-Nampa
RECRUITINGNampa, Idaho, 83687, United States
Contact Email: •••••@•••••
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Saint Alphonsus Cancer Care Center-Ontario
RECRUITINGOntario, Oregon, 97914, United States
Contact Email: •••••@•••••
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Saint Francis Medical Center
RECRUITINGCape Girardeau, Missouri, 63703, United States
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Saint John's Hospital - Healtheast
RECRUITINGMaplewood, Minnesota, 55109, United States
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Salina Regional Health Center
RECRUITINGSalina, Kansas, 67401, United States
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Sanford Bismarck Medical Center
RECRUITINGBismarck, North Dakota, 58501, United States
Contact Email: •••••@•••••
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Sanford Broadway Medical Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Email: •••••@•••••
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Sanford Cancer Center Oncology Clinic
RECRUITINGSioux Falls, South Dakota, 57104, United States
Contact Email: •••••@•••••
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Sanford Joe Lueken Cancer Center
RECRUITINGBemidji, Minnesota, 56601, United States
Contact Email: •••••@•••••
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Sanford Roger Maris Cancer Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Email: •••••@•••••
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Sanford USD Medical Center - Sioux Falls
RECRUITINGSioux Falls, South Dakota, 57117-5134, United States
Contact Email: •••••@•••••
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Sidney Kimmel Cancer Center Washington Township
ACTIVE_NOT_RECRUITINGSewell, New Jersey, 08080, United States
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Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
Contact Email: •••••@•••••
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
Contact Email: •••••@•••••
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Southern Illinois University School of Medicine
RECRUITINGSpringfield, Illinois, 62702, United States
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Springfield Clinic
RECRUITINGSpringfield, Illinois, 62702, United States
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Springfield Memorial Hospital
RECRUITINGSpringfield, Illinois, 62781, United States
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State University of New York Upstate Medical University
RECRUITINGSyracuse, New York, 13210, United States
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The University of Kansas Cancer Center - Olathe
RECRUITINGOlathe, Kansas, 66061, United States
Contact Email: •••••@•••••
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Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITINGBrighton, Michigan, 48114, United States
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Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITINGCanton, Michigan, 48188, United States
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Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITINGChelsea, Michigan, 48118, United States
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Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITINGYpsilanti, Michigan, 48197, United States
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Trinity Health Saint Joseph Mercy Hospital Ann Arbor
RECRUITINGAnn Arbor, Michigan, 48106, United States
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Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITINGPontiac, Michigan, 48341, United States
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Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITINGLivonia, Michigan, 48154, United States
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UC Comprehensive Cancer Center at Silver Cross
RECRUITINGNew Lenox, Illinois, 60451, United States
Contact Email: •••••@•••••
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UCHealth Greeley Hospital
RECRUITINGGreeley, Colorado, 80631, United States
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UCHealth Memorial Hospital Central
RECRUITINGColorado Springs, Colorado, 80909, United States
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UChicago Medicine Northwest Indiana
RECRUITINGCrown Point, Indiana, 46307, United States
Contact Email: •••••@•••••
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UNC Lineberger Comprehensive Cancer Center
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact Email: •••••@•••••
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UPMC Cancer Center at UPMC Northwest
RECRUITINGSeneca, Pennsylvania, 16346, United States
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UPMC Cancer Center-Uniontown
RECRUITINGUniontown, Pennsylvania, 15401, United States
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UPMC Cancer Center-Washington
RECRUITINGWashington, Pennsylvania, 15301, United States
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UPMC Cancer Centers - Arnold Palmer Pavilion
RECRUITINGGreensburg, Pennsylvania, 15601, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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UPMC Hillman Cancer Center - Monroeville
RECRUITINGMonroeville, Pennsylvania, 15146, United States
Contact Email: •••••@•••••
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UPMC Hillman Cancer Center Erie
RECRUITINGErie, Pennsylvania, 16505, United States
Contact Email: •••••@•••••
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UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
RECRUITINGMechanicsburg, Pennsylvania, 17050, United States
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UPMC Pinnacle Cancer Center/Community Osteopathic Campus
RECRUITINGHarrisburg, Pennsylvania, 17109, United States
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UPMC-Johnstown/John P. Murtha Regional Cancer Center
RECRUITINGJohnstown, Pennsylvania, 15901, United States
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UPMC-Passavant Hospital
RECRUITINGPittsburgh, Pennsylvania, 15237, United States
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UPMC-Saint Clair Hospital Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15243, United States
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UPMC-Saint Margaret
RECRUITINGPittsburgh, Pennsylvania, 15215, United States
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UW Cancer Center at ProHealth Care
RECRUITINGWaukesha, Wisconsin, 53188, United States
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UW Health Carbone Cancer Center Rockford
RECRUITINGRockford, Illinois, 61114, United States
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United Hospital
RECRUITINGSaint Paul, Minnesota, 55102, United States
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University Health Truman Medical Center
RECRUITINGKansas City, Missouri, 64108, United States
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University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of Chicago Comprehensive Cancer Center
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
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University of Chicago Medicine-Orland Park
RECRUITINGOrland Park, Illinois, 60462, United States
Contact Email: •••••@•••••
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Kansas Cancer Center - Briarcliff
RECRUITINGKansas City, Missouri, 64116, United States
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University of Kansas Cancer Center - Lee's Summit
RECRUITINGLee's Summit, Missouri, 64064, United States
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University of Kansas Cancer Center - North
RECRUITINGKansas City, Missouri, 64154, United States
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University of Kansas Cancer Center-Overland Park
RECRUITINGOverland Park, Kansas, 66210, United States
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University of Kansas Health System Saint Francis Campus
RECRUITINGTopeka, Kansas, 66606, United States
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University of Kansas Hospital-Indian Creek Campus
RECRUITINGOverland Park, Kansas, 66211, United States
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University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
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University of Maryland/Greenebaum Cancer Center
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Michigan Health - Sparrow Lansing
RECRUITINGLansing, Michigan, 48912, United States
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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Upper Valley Medical Center
RECRUITINGTroy, Ohio, 45373, United States
Contact Email: •••••@•••••
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Upstate Cancer Center at Verona
RECRUITINGVerona, New York, 13478, United States
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VA Palo Alto Health Care System
RECRUITINGPalo Alto, California, 94304, United States
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VCU Massey Cancer Center at Stony Point
RECRUITINGRichmond, Virginia, 23235, United States
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VCU Massey Comprehensive Cancer Center
RECRUITINGRichmond, Virginia, 23298, United States
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Vince Lombardi Cancer Clinic - Oshkosh
RECRUITINGOshkosh, Wisconsin, 54904, United States
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Vince Lombardi Cancer Clinic-Sheboygan
RECRUITINGSheboygan, Wisconsin, 53081, United States
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Vince Lombardi Cancer Clinic-Two Rivers
RECRUITINGTwo Rivers, Wisconsin, 54241, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
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West Virginia University Charleston Division
RECRUITINGCharleston, West Virginia, 25304, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug combo slow advanced head and neck cancer?
- Can immunotherapy boost surgery outcomes in recurrent head and neck cancer?
- Can a Three-Pronged attack shrink Hard-to-Treat head and neck cancers?
- Sharper radiation boost aims to tackle head and neck cancers that return
- New combo attack: immunotherapy plus chemo before surgery for head and neck cancer
- Leftover immunotherapy may boost chemo: new study investigates timing