New drug combo aims to keep head and neck cancer at bay
NCT ID NCT05433116
First seen Dec 08, 2025 · Last updated May 20, 2026 · Updated 21 times
Summary
This study looks at whether adding lenvatinib to pembrolizumab after standard chemoradiation can help prevent head and neck cancer from coming back. About 50 adults with PD-L1 positive advanced cancer will receive either the combination or pembrolizumab alone. The goal is to see if the combo improves how long patients live without the cancer returning.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Gemeinschaftspraxis Hämatologie-Onkologie
Dresden, Saxony, 01307, Germany
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Hospital Chemnitz, Radiation Oncology
Chemnitz, Saxony, 09116, Germany
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Saarland University Medical Center and Saarland University Faculty of Medicine, Clinic for Radiotherapy and Radiooncology
Homburg, Saarland, 66421, Germany
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University Hospital Augsburg, Radiation Oncology
Augsburg, Bavaria, 86156, Germany
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University Hospital Düsseldorf, Radiation Oncology
Düsseldorf, North Rhine-Westphalia, 40225, Germany
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University Hospital Erlangen, Radiation Oncology
Erlangen, Bavaria, 91054, Germany
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University Hospital Frankfurt/M, Center for Radiology
Frankfurt am Main, Hesse, 60590, Germany
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University Hospital Giessen; Ear, nose and throat clinic
Giessen, Hesse, 35392, Germany
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University Hospital Regensburg, Clinic and Polyclinic for Radiotherapy
Regensburg, Bavaria, 93053, Germany
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University Hospital Ulm, Otolaryngology & Head and Neck Surgery
Ulm, Baden-Wurttemberg, 89070, Germany
Conditions
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