New drug cocktail aims to extend life in tough lung cancer
NCT ID NCT06422143
First seen Jun 26, 2026 · Last updated Sep 04, 2026 · Updated 13 times
Summary
This Phase 3 trial tests whether adding a maintenance drug (sacituzumab tirumotecan) after initial chemo-immunotherapy improves survival in people with metastatic squamous non-small cell lung cancer. About 851 participants will receive pembrolizumab plus chemotherapy, then either continue pembrolizumab alone or add the experimental drug. The goal is to see if the combination helps people live longer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pembrolizumab (Keytruda) and sacituzumab tirumotecan (sac-TMT)
- What this could lead to
- If successful, this could offer a new first-line treatment option that extends survival for people with advanced squamous lung cancer.
- What could go wrong
- This is a large Phase 3 trial, but the experimental maintenance drug may not improve survival over standard care. Side effects from the combination could be significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 851 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Aug 2031
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Histologically or cytologically confirmed diagnosis of squamous non-small cell lung cancer (NSCLC) \[Stage IV: M1a, M1b, M1c, American Joint Committee on Cancer Staging Manual, version 8\] * Measurable disease per Response Evaluation Criteria in Solid Tumours (RECIST) 1.1 as assessed by the local site investigator/radiology * Has life expectancy ≥3 months * Has Eastern Cooperative Oncology Group Performance Status (ECOG PS) score of 0 or 1 assessed within 7 days prior to allocation * Archival tumor tissue sample or newly obtained core, incisional, or excisional biopsy of a tumor lesion not previously irradiated has been provided * Human immunodeficiency virus (HIV)-infected participants must have well controlled HIV on antiretroviral therapy (ART) * Participants who are hepatitis B surface antigen (HBsAg)-positive are eligible if they have received hepatitis B virus (HBV) antiviral therapy for at least 4 weeks and have undetectable HBV viral load before allocation * Participants with history of hepatitis C virus (HCV) infection are eligible if HCV viral load is undetectable at screening * Participants who have adverse events (AEs) due to previous anticancer therapies must have recovered to Grade ≤1 or baseline (participants with endocrine-related AEs who are adequately treated with hormone replacement are eligible) * Has adequate organ function * For Maintenance only (prior to randomization): is without disease progression of their NSCLC, as determined by BICR using RECIST 1.1 after completion of study-specified Induction with an evaluable scan at Week 12 or most recent scan before randomization * For Maintenance only (prior to randomization): has ECOG PS of 0 or 1 as assessed at the Prerandomization Visit * For Maintenance only (prior to randomization): all AEs (with the exception of alopecia, Grade ≤2 fatigue, Grade ≤2 peripheral neuropathy, and Grade ≤2 endocrine-related AEs requiring treatment or hormone replacement) have recovered * For Maintenance only (prior to randomization): has not experienced a pneumonitis/interstitial lung disease (ILD) event during the study-specified induction Exclusion Criteria: * Diagnosis of small cell lung cancer or, for mixed tumors, presence of small cell elements * History of documented severe dry eye syndrome, severe Meibomian gland disease and/or blepharitis, or severe corneal disease that prevents/delays corneal healing * Active inflammatory bowel disease requiring immunosuppressive medication or previous history of inflammatory bowel disease (eg, Crohn's disease, ulcerative colitis, or chronic diarrhea) * Has uncontrolled, significant cardiovascular disease or cerebrovascular disease including New York Heart Association Class III or IV congestive heart failure, unstable angina, myocardial infarction, uncontrolled symptomatic arrhythmia, prolongation of QTcF interval to \>480 ms, and other serious cardiovascular and cerebrovascular diseases within 6 months before study intervention * HIV-infected participants who have been newly diagnosed or with a history of Kaposi's sarcoma and/or Multicentric Castleman's Disease * Received prior systemic chemotherapy or other targeted or biological antineoplastic therapy for their metastatic NSCLC. Note: Prior treatment with chemotherapy and/or radiation as a part of neoadjuvant or adjuvant therapy or chemoradiation therapy for nonmetastatic NSCLC is allowed as long as therapy was completed at least 12 months before diagnosis of metastatic NSCLC * Received prior therapy with an anti-programmed cell death 1 protein (PD-1), anti-programmed cell death ligand 1 (PD-L1), or anti programmed cell death ligand 2 (PD-L2) agent, or with an agent directed to another stimulatory or coinhibitory T-cell receptor (eg, cytotoxic T lymphocyte-associated protein 4, OX-40, CD137). Note: Prior treatment with an anti-PD-1 or anti-PD-L1 agent for nonmetastatic NSCLC is allowed as long as therapy was completed at least 12 months before diagnosis of metastatic NSCLC * Received prior treatment with a trophoblast cell-surface antigen 2 (TROP2)-targeted antidrug conjugate (ADC) * Received radiation therapy to the lung that is \>30 Gray within 6 months of start of study intervention * Received prior radiotherapy within 2 weeks of start of study intervention, or radiation-related toxicities, requiring corticosteroids * Received a live or live-attenuated vaccine within 30 days before the first dose of study intervention * Participants who have not adequately recovered from major surgery or have ongoing surgical complications * Received prior treatment with a topoisomerase I inhibitor-containing ADC * Is currently receiving a strong inducer/inhibitor of CYP3A4 that cannot be discontinued for the duration of the study (the required washout period before starting sac-TMT is 2 weeks) * Has a known additional malignancy that is progressing or has required active treatment within the past 3 years. * Has known central nervous system (CNS) metastases/carcinomatous meningitis * Severe hypersensitivity (≥Grade 3) to study intervention and/or any of its excipients or to another biologic therapy * Active autoimmune disease that has required systemic treatment in the past 2 years (replacement therapy \[eg, thyroxine, insulin, or physiologic corticosteroid\] is allowed) * Has a history of (noninfectious)pneumonitis/ILD that required steroids, has current pneumonitis/ILD, or has suspected ILD or pneumonitis that cannot be ruled out by standard diagnostic assessments at Screening * Active infection requiring systemic therapy * History of allogeneic tissue/solid organ transplant
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Metastatic squamous non-small cell lung cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
172 sites in 24 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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Aichi Cancer Center ( Site 2502)
RECRUITINGNagoya, Aichi-ken, 464-8681, Japan
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Allina Health Cancer Institute - Abbott Northwestern Hospital ( Site 0146)
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1800)
RECRUITINGAnkara, 06800, Turkey (Türkiye)
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Army Medical Center of People's Liberation Army-respiratory ( Site 2426)
ACTIVE_NOT_RECRUITINGChongqing, Chongqing Municipality, 400042, China
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Asan Medical Center ( Site 2105)
RECRUITINGSeoul, 05505, South Korea
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Azienda Ospedaliera Maggiore della Carita ( Site 1416)
RECRUITINGNovara, 28100, Italy
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Azienda Ospedaliera S. Giovanni Addolorata-Oncologia Medica ( Site 1409)
RECRUITINGRome, Lazio, 00184, Italy
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Azienda Ospedaliera Spedali Civili di Brescia-Oncology ( Site 1414)
RECRUITINGBrescia, 25123, Italy
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Bacs-Kiskun Varmegyei Oktatokorhaz ( Site 1100)
RECRUITINGKecskemét, Bács-Kiskun county, 6000, Hungary
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Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 2300)
RECRUITINGDusit, Bangkok, 10300, Thailand
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Beijing Cancer Hospital ( Site 2411)
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 100142, China
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Beijing Cancer hospital-intrathoratic deparmtment II ( Site 2410)
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 100142, China
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Bialostockie Centrum Onkologii ( Site 1520)
RECRUITINGBialystok, Podlaskie Voivodeship, 15-027, Poland
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Bradford Hill Norte ( Site 0420)
RECRUITINGAntofagasta, 1240000, Chile
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Bradfordhill-Clinical Area ( Site 0407)
RECRUITINGSantiago, Region M. de Santiago, 8420383, Chile
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Burjeel Medical City ( Site 2600)
COMPLETEDAbu Dhabi, Abu Dhabi Emirate, 92510, United Arab Emirates
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CARTI Cancer Center ( Site 0006)
RECRUITINGLittle Rock, Arkansas, 72205, United States
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CHD Vendee ( Site 0901)
RECRUITINGLa Roche-sur-Yon, Vendee, 85000, France
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CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 1703)
RECRUITINGSantiago de Compostela, Galicia, 15706, Spain
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Cabinet Medical Oncomed ( Site 2005)
RECRUITINGTimișoara, Timiș County, 300239, Romania
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Cancer Institute Hospital of JFCR ( Site 2500)
RECRUITINGKoto, Tokyo, 135-8550, Japan
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Capital Health Medical Center - Hopewell ( Site 0034)
RECRUITINGPennington, New Jersey, 08534, United States
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Cardiomed SRL Cluj-Napoca ( Site 2002)
RECRUITINGCluj-Napoca, Cluj, 400015, Romania
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Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 0106)
RECRUITINGTrois-Rivières, Quebec, G8Z 3R9, Canada
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Centricity Research Columbus Cancer Center ( Site 0111)
COMPLETEDColumbus, Georgia, 31904, United States
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Centro Cancerológico del Caribe (CECAC) ( Site 0509)
RECRUITINGBarranquilla, Atlántico, 080002, Colombia
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Centro Ricerche Cliniche di Verona s.r.l. c/o Policlinico G.B.Rossi ( Site 1415)
RECRUITINGVerona, 37134, Italy
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Centro de Investigación del Maule ( Site 0419)
COMPLETEDTalca, Maule Region, 3481349, Chile
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Centrul Medical Medicover Victoria ( Site 2000)
RECRUITINGBucharest, Bucharest, 010626, Romania
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Centrul de Oncologie Sfantul Nectarie-Medical ( Site 2004)
RECRUITINGCraiova, Dolj, 200542, Romania
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Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1503)
RECRUITINGBydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland
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Chang Gung Medical Foundation-Linkou Branch-Clinic of Chest Medicine ( Site 2202)
RECRUITINGTaoyuan, 333, Taiwan
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Chang Gung Memorial Hospital at Kaohsiung ( Site 2207)
RECRUITINGKaohsiung City, 83301, Taiwan
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Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 1003)
RECRUITINGBerlin, 13353, Germany
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Chiba University Hospital ( Site 2517)
RECRUITINGChiba, 260-8677, Japan
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Chungnam national university hospital-Department of Internal Medicine ( Site 2107)
RECRUITINGDaejeon, Taejon-Kwangyokshi, 35015, South Korea
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City Hospital, Nottingham University Hospitals NHS Trust-NCCTT ( Site 1911)
RECRUITINGNottingham, Nottinghamshire, NG5 1PB, United Kingdom
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Cleveland Clinic Abu Dhabi ( Site 2650)
COMPLETEDAbu Dhabi, Abu Dhabi Emirate, 112412, United Arab Emirates
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Clinica Polisano ( Site 2008)
RECRUITINGSibiu, 550253, Romania
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Clinique Clairval ( Site 0904)
RECRUITINGMarseille, Bouches-du-Rhone, 13009, France
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Clínica San Antonio ( Site 0606)
RECRUITINGTrujillo, La Libertad, 13008, Peru
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Clínicas AUNA Sede Chiclayo ( Site 0604)
ACTIVE_NOT_RECRUITINGChiclayo, Lambayeque, 14001, Peru
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Dokkyo Medical University Hospital ( Site 2527)
RECRUITINGShimotsuga-gun, Tochigi, 321-0293, Japan
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Ehime University Hospital ( Site 2511)
RECRUITINGTōon, Ehime, 791-0295, Japan
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FALP ( Site 0409)
RECRUITINGSantiago, Region M. de Santiago, 7500921, Chile
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FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0500)
RECRUITINGBogotá, Bogota D.C., 110131, Colombia
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Faculty of Medicine - Khon Kaen University ( Site 2305)
RECRUITINGMuang, Changwat Khon Kaen, 40002, Thailand
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Faculty of Medicine Siriraj Hospital ( Site 2301)
RECRUITINGBangkoknoi, Bangkok, 10700, Thailand
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Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 0802)
RECRUITINGOlomouc, 779 00, Czechia
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First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 2402)
ACTIVE_NOT_RECRUITINGHuai'an, Jiangsu, 223300, China
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Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1404)
RECRUITINGMilan, Lombardy, 20133, Italy
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Fondazione IRCCS Policlinico San Matteo-Oncology ( Site 1410)
RECRUITINGPavia, 27100, Italy
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Fondazione IRCCS San Gerardo dei Tintori-Oncologia ( Site 1412)
RECRUITINGMonza, Lombardy, 20900, Italy
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Fujian Provincial Cancer Hospital ( Site 2419)
ACTIVE_NOT_RECRUITINGFuzhou, Fujian, 350014, China
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Fujita Health University Hospital ( Site 2515)
RECRUITINGToyoake, Aichi-ken, 470-1192, Japan
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Fundacion Intecnus ( Site 0205)
RECRUITINGBariloche, Río Negro Province, R8402APU, Argentina
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Fundación Valle del Lili-Oncology CIC ( Site 0505)
RECRUITINGCali, Valle del Cauca Department, 760032, Colombia
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GEFOS Gesellschaft f. onkologische Studien ( Site 1005)
RECRUITINGDortmund, North Rhine-Westphalia, 44309, Germany
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Gazi Universitesi-Oncology ( Site 1804)
RECRUITINGAnkara, 06560, Turkey (Türkiye)
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Gunma Prefectural Cancer Center ( Site 2510)
RECRUITINGŌta, Gunma, 373-8550, Japan
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Hacettepe Universite Hastaneleri-oncology hospital ( Site 1801)
RECRUITINGAnkara, 06230, Turkey (Türkiye)
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Harbin Medical University Cancer Hospital-oncology of department ( Site 2415)
ACTIVE_NOT_RECRUITINGHarbin, Heilongjiang, 150000, China
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Henan Cancer Hospital-Pneumology department ( Site 2423)
ACTIVE_NOT_RECRUITINGZhengzhou, Henan, 450008, China
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Hirosaki University Hospital ( Site 2514)
RECRUITINGHirosaki, Aomori, 036-8563, Japan
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Hospital Aleman-Oncology ( Site 0202)
RECRUITINGBuenos Aires, C1118AAT, Argentina
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Hospital Insular de Gran Canaria-Oncology ( Site 1701)
RECRUITINGLas Palmas de Gran Canaria, Las Palmas, 35016, Spain
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Hospital Militar Central Coronel Luis Arias Schereiber ( Site 0602)
RECRUITINGLima, 15076, Peru
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Hospital Nossa Senhora da Conceição ( Site 0300)
RECRUITINGPorto Alegre, Rio Grande do Sul, 91350-200, Brazil
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Hospital Paulistano ( Site 0307)
RECRUITINGSão Paulo, 01321-001, Brazil
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Hospital Quirón Málaga ( Site 1704)
RECRUITINGMálaga, Malaga, 29004, Spain
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Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1700)
RECRUITINGBarcelona, 08035, Spain
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Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 1702)
RECRUITINGMadrid, 28040, Spain
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Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 1705)
RECRUITINGSeville, 41014, Spain
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Hospital de Base de São José do Rio Preto ( Site 0310)
RECRUITINGSão José do Rio Preto, São Paulo, 15090-000, Brazil
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Hospital do Cancer de Pernambuco ( Site 0312)
RECRUITINGRecife, Pernambuco, 50040-000, Brazil
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Hôpital Robert Schuman ( Site 0907)
RECRUITINGVantoux, Lorraine, 57070, France
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Hôpital Saint-Louis ( Site 0906)
COMPLETEDParis, 75475, France
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Institut de Cancérologie de l'Ouest ( Site 0908)
RECRUITINGAngers, Maine-et-Loire, 49055, France
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Instituto Alexander Fleming ( Site 0203)
RECRUITINGCiudad Autónoma de Buenos Aires, Buenos Aires, C1426ANZ, Argentina
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Instituto Médico Río Cuarto ( Site 0204)
RECRUITINGRío Cuarto, Córdoba Province, X5800AEV, Argentina
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Instituto de Investigaciones Clínicas Mar del Plata ( Site 0200)
RECRUITINGMar del Plata, Buenos Aires, B7600FZO, Argentina
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Instituto de Oncologia Saint Gallen ( Site 0304)
RECRUITINGSanta Cruz do Sul, Rio Grande do Sul, 96830-180, Brazil
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Instytut Gruzlicy i Chorob Pluc w Warszawie ( Site 1523)
RECRUITINGWarsaw, Masovian Voivodeship, 01-138, Poland
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Intermountain Health Cancer Center Lutheran Hospital ( Site 0119)
RECRUITINGGolden, Colorado, 80401, United States
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Intermountain Health St. Mary's Regional Hospital ( Site 0116)
RECRUITINGGrand Junction, Colorado, 81501, United States
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Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0311)
RECRUITINGPorto Alegre, Rio Grande do Sul, 90020-090, Brazil
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Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1408)
RECRUITINGRozzano, Milano, 20089, Italy
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Istituto Nazionale Tumori IRCCS Fondazione Pascale-Oncologia clinica sperimentale Toraco-Polmonare ( Site 1401)
RECRUITINGNaples, Campania, 80131, Italy
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Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1402)
RECRUITINGRome, Roma, 00144, Italy
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Izmir Atatürk Training and Research Hospital ( Site 1810)
RECRUITINGIzmir, 35360, Turkey (Türkiye)
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Jilin Province Tumor Hospital-GCP office ( Site 2413)
ACTIVE_NOT_RECRUITINGChangchun, Jilin, 130000, China
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John Theurer Cancer Center at Hackensack University Medical Center ( Site 0035)
RECRUITINGHackensack, New Jersey, 07601, United States
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Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház-Onkologiai Kozpont ( Site 1103)
RECRUITINGSzolnok, Jász-Nagykun-Szolnok, 5004, Hungary
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Kanagawa Cancer Center ( Site 2504)
RECRUITINGYokohama, Kanagawa, 241-8515, Japan
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Kanagawa Cardiovascular and Respiratory Center ( Site 2518)
RECRUITINGYokohama, Kanagawa, 236-0051, Japan
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Kanazawa University Hospital ( Site 2513)
RECRUITINGKanazawa, Ishikawa-ken, 920-8641, Japan
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Kansai Medical University Hospital ( Site 2503)
RECRUITINGHirakata, Osaka, 573-1191, Japan
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Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 0100)
RECRUITINGKingston, Ontario, K7L 2V7, Canada
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Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0710)
RECRUITINGVienna, 1210, Austria
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Klinik Hietzing ( Site 0740)
RECRUITINGVienna, 1130, Austria
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Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung ( Site 1001)
RECRUITINGEssen, North Rhine-Westphalia, 45136, Germany
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Kobe Minimally Invasive Cancer Center ( Site 2528)
RECRUITINGKobe, Hyōgo, 650-0046, Japan
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Kochi Medical School Hospital ( Site 2526)
RECRUITINGNankoku, Kochi, 783-8505, Japan
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Korea University Guro Hospital-Internal Medicine ( Site 2103)
RECRUITINGSeoul, 08308, South Korea
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Kyung Hee University Hospital ( Site 2101)
RECRUITINGSeoul, 02447, South Korea
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Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2102)
RECRUITINGDeagu, Taegu-Kwangyokshi, 41404, South Korea
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Lampang Cancer Hospital ( Site 2304)
RECRUITINGLampang, Changwat Lampang, 52000, Thailand
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Lotus-Med ( Site 2009)
RECRUITINGBucharest, 012292, Romania
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Mackay Memorial Hospital-Chest Medicine ( Site 2201)
RECRUITINGTaipei, 10449, Taiwan
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Maharaj Nakorn Chiang Mai Hospital ( Site 2302)
RECRUITINGMuang, Chiang Mai, 50200, Thailand
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Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0800)
RECRUITINGBrno, Brno-mesto, 656 53, Czechia
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Mays Cancer Center ( Site 0132)
COMPLETEDSan Antonio, Texas, 78229, United States
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McGill University Health Centre ( Site 0103)
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
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Medipol Mega Universite Hastanesi-oncology ( Site 1811)
RECRUITINGStanbul, Istanbul, 34214, Turkey (Türkiye)
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Memorial Hermann Cancer Center ( Site 0015)
RECRUITINGHouston, Texas, 77030, United States
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Memorial Kayseri Hastanesi ( Site 1805)
RECRUITINGKayseri, 38010, Turkey (Türkiye)
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Mersin Sehir Eğitim ve Araştırma Hastanesi-Oncology ( Site 1808)
RECRUITINGMersin, 33240, Turkey (Türkiye)
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Mid Florida Hematology and Oncology Center ( Site 0109)
COMPLETEDOrange City, Florida, 32763, United States
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Multiscan-Onkologicke a radiologicke centrum Multiscan Pardubice ( Site 0804)
RECRUITINGPardubice, Pardubice Region, 532 03, Czechia
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Nagoya University Hospital ( Site 2519)
RECRUITINGNagoya, Aichi-ken, 466-8560, Japan
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Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 1500)
RECRUITINGWarsaw, Masovian Voivodeship, 02-781, Poland
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National Cancer Center Hospital East ( Site 2501)
RECRUITINGKashiwa, Chiba, 277-8577, Japan
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National Center for Global Health and Medicine ( Site 2516)
RECRUITINGShinjuku, Tokyo, 162-8655, Japan
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National Cheng Kung University Hospital ( Site 2205)
RECRUITINGTainan, 704, Taiwan
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National Hospital Organization Kyushu Medical Center ( Site 2509)
RECRUITINGFukuoka, 810-8563, Japan
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National Hospital Organization Ureshino Medical Center ( Site 2524)
RECRUITINGUreshino, Saga-ken, 843-0393, Japan
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National Hospital Organization Yamaguchi Ube Medical Center ( Site 2523)
RECRUITINGUbe, Yamaguchi, 755-0241, Japan
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National Taiwan University Cancer Center (NTUCC) ( Site 2209)
RECRUITINGTaipei City, Taipei, 106, Taiwan
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National Taiwan University Hospital-Oncology ( Site 2208)
RECRUITINGTaipei, 10002, Taiwan
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Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni oddeleni ( Site 0803)
RECRUITINGOstrava-Vitkovice, Ostrava Mesto, 703 00, Czechia
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New Mexico Oncology Hematology Consultants Ltd. ( Site 0123)
COMPLETEDAlbuquerque, New Mexico, 87109, United States
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Niigata Cancer Center Hospital ( Site 2505)
RECRUITINGNiigata, 951-8566, Japan
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North West Cancer Centre ( Site 1908)
RECRUITINGLondonderry, Derry and Strabane, BT47 6SB, United Kingdom
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Northern Jiangsu People's Hospital-General Surgery Department ( Site 2403)
ACTIVE_NOT_RECRUITINGYangzhou, Jiangsu, 225001, China
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Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0001)
COMPLETEDMarietta, Georgia, 30060, United States
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ONCOCENTRO APYS-ACEREY ( Site 0400)
RECRUITINGViña del Mar, Valparaiso, 2520598, Chile
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Oncologos del Occidente ( Site 0504)
RECRUITINGPereira, Risaralda Department, 660001, Colombia
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Oncology Consultants P.A. ( Site 0124)
RECRUITINGHouston, Texas, 77030, United States
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Oncosalud-Clinical Research ( Site 0600)
RECRUITINGLima, 15036, Peru
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Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0720)
RECRUITINGLinz, Upper Austria, 4020, Austria
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Országos Korányi Pulmonológiai Intézet ( Site 1104)
RECRUITINGBudapest, 1121, Hungary
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Osaka Prefectural Hospital Organization Osaka International Cancer Institute ( Site 2506)
RECRUITINGOsaka, 541-8567, Japan
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Ospedale San Martino ( Site 1407)
RECRUITINGGenova, 16132, Italy
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Ospedale di Circolo e Fondazione Macchi Varese-Oncology ( Site 1413)
COMPLETEDVarese, 21100, Italy
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Peking Union Medical College Hospital ( Site 2412)
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 100730, China
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Petz Aladar Egyetemi Oktato Korhaz ( Site 1101)
RECRUITINGGyőr, Győr-Moson-Sopron, 9024, Hungary
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Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0402)
RECRUITINGSantiago, Region M. de Santiago, 8330024, Chile
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Prapokklao Hospital ( Site 2306)
RECRUITINGMueang, Changwat Chanthaburi, 22000, Thailand
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Pusan National University Hospital ( Site 2100)
RECRUITINGBusan, Pusan-Kwangyokshi, 49241, South Korea
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Pusan National University Yangsan Hospital ( Site 2104)
RECRUITINGYangsan, Kyongsangnam-do, 50612, South Korea
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Rabin Medical Center ( Site 1303)
RECRUITINGPetah Tikva, 4941492, Israel
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Rambam Health Care Campus-Oncology Division ( Site 1302)
COMPLETEDHaifa, 3109601, Israel
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Reformatus Pulmonologiai Centrum ( Site 1102)
RECRUITINGTörökbálint, Pest County, 2045, Hungary
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Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 1513)
COMPLETEDGrudziądz, Kuyavian-Pomeranian Voivodeship, 86-300, Poland
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Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0122)
RECRUITINGBurbank, California, 91505, United States
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SC ONCO CARD SRL ( Site 2007)
RECRUITINGBrasov, 500052, Romania
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SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 2001)
RECRUITINGFlorești, Cluj, 407280, Romania
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SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1006)
RECRUITINGGera, Thuringia, 07548, Germany
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Sainte Catherine Institut du Cancer Avignon Provence ( Site 0902)
RECRUITINGAvignon, Vaucluse, 84000, France
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Saiseikai Matsusaka Municipal Hospital ( Site 2522)
RECRUITINGMatsusaka, Mie-ken, 515-8544, Japan
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Saitama Prefectural Cancer Center ( Site 2512)
RECRUITINGKitaadachi-gun, Saitama, 362-0806, Japan
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Samsun Medical Park Hastanesi-medical oncology ( Site 1806)
RECRUITINGSamsun, 55200, Turkey (Türkiye)
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Sanatorio Parque ( Site 0201)
RECRUITINGRosario, Santa Fe Province, S2000DSV, Argentina
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Sendai Kousei Hospital ( Site 2507)
RECRUITINGSendai, Miyagi, 981-0914, Japan
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Shaare Zedek Medical Center ( Site 1300)
RECRUITINGJerusalem, 9103102, Israel
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Shanghai East Hospital ( Site 2428)
ACTIVE_NOT_RECRUITINGShanghai, Shanghai Municipality, 200120, China
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Shanghai Pulmonary Hospital ( Site 2427)
ACTIVE_NOT_RECRUITINGShanghai, Shanghai Municipality, 200433, China
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Sharp Memorial Hospital ( Site 9544)
RECRUITINGSan Diego, California, 92123, United States
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Sheba Medical Center ( Site 1301)
RECRUITINGRamat Gan, 5265601, Israel
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Sichuan Cancer hospital. ( Site 2421)
ACTIVE_NOT_RECRUITINGChengdu, Sichuan, 610042, China
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Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-Medical Oncology ( Site 2407)
ACTIVE_NOT_RECRUITINGHangzhou, Zhejiang, 310016, China
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Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501)
ACTIVE_NOT_RECRUITINGValledupar, Cesar Department, 200001, Colombia
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Songklanagarind hospital ( Site 2303)
RECRUITINGHat Yai, Changwat Songkhla, 90110, Thailand
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Southeastern Regional Medical Center ( Site 0004)
COMPLETEDNewnan, Georgia, 30265, United States
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Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 2416)
ACTIVE_NOT_RECRUITINGGuangzhou, Guangdong, 510515, China
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St Bartholomew's Hospital ( Site 1901)
RECRUITINGLondon, London, City of, EC1A7BE, United Kingdom
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St Luke's University Health Network ( Site 0017)
RECRUITINGBethlehem, Pennsylvania, 18015, United States
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St. James's Hospital ( Site 1200)
RECRUITINGDublin, D08 A978, Ireland
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St. Marianna University Hospital ( Site 2521)
RECRUITINGKawasaki, Kanagawa, 216-8511, Japan
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St. Marys Hospital Center ( Site 0105)
RECRUITINGMontreal, Quebec, H3T 1M5, Canada
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Standort Penzing der Klinik Ottakring-Abteilung für Atemwegs-und Lungenkrankheiten ( Site 0730)
RECRUITINGVienna, 1140, Austria
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Szpital Specjalistyczny im. Henryka Klimontowicza ( Site 1507)
COMPLETEDGorlice, Lesser Poland Voivodeship, 38-300, Poland
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Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1515)
RECRUITINGKrakow, Lesser Poland Voivodeship, 31-826, Poland
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Szpital Wojewódzki w Koszalinie. ( Site 1517)
RECRUITINGPoland, West Pomeranian Voivodeship, 75-581, Poland
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Taichung Veterans General Hospital ( Site 2204)
RECRUITINGTaichung, 407, Taiwan
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Taizhou Hospital of Zhejiang Province ( Site 2430)
ACTIVE_NOT_RECRUITINGTaizhou, Zhejiang, 317000, China
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Takarazuka City Hospital ( Site 2508)
RECRUITINGTakarazuka, Hyōgo, 665-0827, Japan
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Taoyuan General Hospital ( Site 2203)
RECRUITINGTaoyuan City, Taoyuan, 33004, Taiwan
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The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 2425)
ACTIVE_NOT_RECRUITINGÜrümqi, Xinjiang, 830000, China
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The Catholic University of Korea, Incheon St. Mary's Hospital ( Site 2106)
RECRUITINGBupyeong-gu, Incheon, 21431, South Korea
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The First Affiliated Hospital of Guangzhou Medical University ( Site 2417)
ACTIVE_NOT_RECRUITINGGuangzhou, Guangdong, 510160, China
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The First Affiliated Hospital of Wenzhou Medical University-Respiratory department ( Site 2409)
ACTIVE_NOT_RECRUITINGWenzhou, Zhejiang, 325015, China
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The First Affiliated hospital of Xiamen University-oncology ( Site 2420)
ACTIVE_NOT_RECRUITINGXiamen, Fujian, 361003, China
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The First Hospital of Jilin University-Oncology ( Site 2414)
ACTIVE_NOT_RECRUITINGChangchun, Jilin, 130021, China
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The First affiliated hospital of Nanchang University (Xianghu campus) ( Site 2404)
ACTIVE_NOT_RECRUITINGNanchang, Jiangxi, 330209, China
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The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2405)
ACTIVE_NOT_RECRUITINGNanchang, Jiangxi, 330006, China
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The Second Xiangya Hospital of Central South University-Oncology ( Site 2418)
ACTIVE_NOT_RECRUITINGChangsha, Hunan, 410011, China
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The first Affiliated Hospital, Zhejiang University School of Medicine-Respiratory Department ( Site 2406)
ACTIVE_NOT_RECRUITINGHangzhou, Zhejiang, 310000, China
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Thomas Jefferson University - Clinical Research Institute ( Site 0147)
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Toho University Omori Medical Center ( Site 2520)
RECRUITINGŌta-ku, Tokyo, 143-8541, Japan
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Tohoku University Hospital ( Site 2525)
RECRUITINGSendai, Miyagi, 980-8574, Japan
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Tongji Hospital Tongji Medical,Science & Technology ( Site 2424)
ACTIVE_NOT_RECRUITINGWuhan, Hubei, 430000, China
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Torbay Hospital ( Site 1906)
RECRUITINGTorquay, Devon, TQ2 7AA, United Kingdom
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Trinity Health Saint Joseph Mercy Hospital Ann Arbor ( Site 9552)
RECRUITINGYpsilanti, Michigan, 48197, United States
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University of Chicago Medical Center ( Site 0145)
RECRUITINGChicago, Illinois, 60637, United States
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University of New Mexico Comprehensive Cancer Center ( Site 0135)
RECRUITINGAlbuquerque, New Mexico, 87131, United States
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Universitätsklinikum Schleswig-Holstein-Pneumologie ( Site 1000)
RECRUITINGLübeck, Schleswig-Holstein, 23538, Germany
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Uniwersytecki Szpital Kliniczny Nr 4 w Lublinie ( Site 1518)
RECRUITINGLublin, Lublin Voivodeship, 20-090, Poland
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Vencer Centro de Pesquisa Clínica ( Site 0309)
RECRUITINGTeresina, Piauí, 64049-200, Brazil
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Washington Hospital Center ( Site 0037)
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Waterloo Regional Health Network (WRHN) ( Site 0153)
RECRUITINGKitchener, Ontario, N2G 1G3, Canada
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West China Hospital, Sichuan University ( Site 2422)
ACTIVE_NOT_RECRUITINGChengdu, Sichuan, 610041, China
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Wielkopolskie Centrum Pulmonologii i Torakochirurgii-Oddzial Onkologii Klinicznej z Pododdzialem Dz ( Site 1510)
RECRUITINGPoznań, Lower Silesian Voivodeship, 60-569, Poland
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Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1501)
RECRUITINGPrzemyśl, Podkarpackie Voivodeship, 37-700, Poland
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Zala Megyei Szent Rafael Kórház ( Site 1110)
RECRUITINGZalaegerszeg, Zala County, 8900, Hungary
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Zhejiang Cancer Hospital-Breast Oncology ( Site 2408)
ACTIVE_NOT_RECRUITINGHangzhou, Zhejiang, 310022, China
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