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New combo attack targets hard-to-treat lung cancer mutation

NCT ID NCT05751187

First seen Mar 18, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This study tests whether adding two targeted drugs (pembrolizumab and bevacizumab) to standard chemotherapy can shrink tumors or slow cancer growth in people with advanced non-squamous lung cancer that has a specific EGFR exon 20 insertion mutation. The trial enrolled 54 adults whose cancer had spread and could not be surgically removed. Researchers measured how many patients responded to treatment and how long they lived without the cancer getting worse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shanghai Chest Hospital

    Shanghai, China

Conditions

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