New combo therapy offers hope for Tough-to-Treat lymphoma
NCT ID NCT05934448
First seen Mar 09, 2026 · Last updated Apr 30, 2026 · Updated 2 times
Summary
This study tests whether adding the drug pembrolizumab to standard CAR-T cell therapy can improve outcomes for people with primary mediastinal B-cell lymphoma that has returned or not responded to prior treatment. About 35 adults will receive the combination and be followed for 6 months to see if their cancer disappears completely. The goal is to find a more effective option for this rare and aggressive blood cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
Contact
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact
Conditions
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