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New combo therapy hopes to restore arm movement in kids after stroke

NCT ID NCT07244042

Symptom relief Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a special stretching technique (PNF) to a standard therapy (modified CIMT) can better improve arm and hand function in children who have had a stroke. Twenty children aged 5 to 13 will be split into two groups: one gets CIMT alone, the other gets CIMT plus PNF. Over six weeks, researchers will measure how often and how well they use their affected arm in daily life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Modified constraint-induced movement therapy (CIMT) and proprioceptive neuromuscular facilitation (PNF) techniques
What this could lead to
If successful, this could point toward a more effective rehabilitation approach to improve arm and hand function in children after a stroke.
What could go wrong
This is a very small, early-stage trial with only 20 participants, so results may not apply to all children. The therapies are non-invasive and low-risk, but the added benefit of PNF is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 to 13 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Paeds Patients with confirmed diagnosis of Stroke * Children between age 5 to 13 years * Modified Ashworth Scale spasticity level 1 and 2. * Patients having Manual Ability Classification System Score between 3 to 6. * GMFCS level 1 and 2 * Patient having in affected upper extremity at least 20◦ of active wrist extension starting from the full flexion, 10◦ of active extension or abduction in the thumb, and 10◦ of active extension in the metacarpophalangeal and interphalangeal joints of the other fingers Exclusion Criteria: * Patients with epilepsy or seizure disorder * Patients with history of botulinum toxin injection, cognitive impairment, fracture and any surgical procedure in upper extremity

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Conditions

The condition(s) this trial relates to.

pediatric arterial ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pediatric stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Imran Amjad

    RECRUITING

    Lahore, Punjab Province, 5400, Pakistan

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