New study aims to uncover hidden causes of low blood sugar in kids
NCT ID NCT07533318
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will look at 50 children from birth to age 18 who have persistent or repeated low blood sugar. Researchers at Sohag University Hospital will use a step-by-step approach to find endocrine, metabolic, or genetic reasons for the condition. The goal is to improve early diagnosis and prevent serious complications like seizures or brain injury.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors identify hidden causes of persistent low blood sugar in children, leading to earlier and more accurate diagnoses.
- What could go wrong
- This is an observational study with only 50 participants at one hospital, so findings may not apply to all children. It aims to understand causes, not test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients from birth up to 18 years of life, presented with persistent and recurrent hypoglycemia, will be included in the study
- Ages
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1 day to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients from birth up to 18 years of life who presented with persistent and recurrent hypoglycemia, will be included in the study Persistent hypoglycemia (PH) is that persist beyond 3 days or Per the AAP guidelines, if it is not possible to maintain a glucose concentration \>45 mg/dL after 24 hours with using a GIR rate of 5-8 mg/kg/min (5,6) Recurrent hypoglycemia is the occurrence of more than 2 episodes of low blood sugar, often associated with symptomatic neuroglycopenia. Exclusion Criteria: * Transient hypoglycemia:e.g Neonate:e.g 1. Infant of a diabetic mother 2. Prematurity 3. Intra-uterine growth retardation 4. Perinatal stress ( infection/sepsis, asphyxia, hypothermia, and respiratory distress) 5. Maternal beta blocker use Infant and Childhood:e.g <!-- --> 1. Malnutrition (marasmus or kwashiorkor) 2. Illness ( gastroenteritis, vomiting, or diarrhea leading to inadequate intake ) 3. Prolonged exercise/fasting 4. Diabetic patient on insulin therapy 5. Medications/ toxins: accidental ingestion of diabetes medication, alcohol, or aspirin 6. Factitious hypoglycemia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Pediatric department, Sohag University Hospital
Sohag, Sohag Governorate, 82524, Egypt
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