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New study aims to uncover hidden causes of low blood sugar in kids

NCT ID NCT07533318

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will look at 50 children from birth to age 18 who have persistent or repeated low blood sugar. Researchers at Sohag University Hospital will use a step-by-step approach to find endocrine, metabolic, or genetic reasons for the condition. The goal is to improve early diagnosis and prevent serious complications like seizures or brain injury.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify hidden causes of persistent low blood sugar in children, leading to earlier and more accurate diagnoses.
What could go wrong
This is an observational study with only 50 participants at one hospital, so findings may not apply to all children. It aims to understand causes, not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients from birth up to 18 years of life, presented with persistent and recurrent hypoglycemia, will be included in the study

Ages

1 day to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients from birth up to 18 years of life who presented with persistent and recurrent hypoglycemia, will be included in the study Persistent hypoglycemia (PH) is that persist beyond 3 days or Per the AAP guidelines, if it is not possible to maintain a glucose concentration \>45 mg/dL after 24 hours with using a GIR rate of 5-8 mg/kg/min (5,6) Recurrent hypoglycemia is the occurrence of more than 2 episodes of low blood sugar, often associated with symptomatic neuroglycopenia. Exclusion Criteria: * Transient hypoglycemia:e.g Neonate:e.g 1. Infant of a diabetic mother 2. Prematurity 3. Intra-uterine growth retardation 4. Perinatal stress ( infection/sepsis, asphyxia, hypothermia, and respiratory distress) 5. Maternal beta blocker use Infant and Childhood:e.g <!-- --> 1. Malnutrition (marasmus or kwashiorkor) 2. Illness ( gastroenteritis, vomiting, or diarrhea leading to inadequate intake ) 3. Prolonged exercise/fasting 4. Diabetic patient on insulin therapy 5. Medications/ toxins: accidental ingestion of diabetes medication, alcohol, or aspirin 6. Factitious hypoglycemia

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Pediatric department, Sohag University Hospital

    Sohag, Sohag Governorate, 82524, Egypt

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