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Birth control Pills' hormone effects in PCOS teens measured

NCT ID NCT07161440

Knowledge-focused Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study measured steroid hormone levels in 56 adolescents and young women with PCOS before and after 6 months of oral contraceptive treatment. Researchers used a precise lab method to track changes in hormones like testosterone. The goal was to better understand how birth control pills affect hormone profiles in this age group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
oral contraceptive pills
What this could lead to
If successful, this could help doctors better understand how birth control pills affect hormone levels in young women with PCOS.
What could go wrong
This is a small, completed observational study, not a treatment trial. Results may not apply to all PCOS patients or lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

56 people

The number who actually took part.

Started

Jan 2021

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adolescent females aged 13 to 21 years diagnosed with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria. All participants were evaluated at the Istanbul Faculty of Medicine between 2020 and 2021. Baseline serum steroid profiles were analyzed using LC-MS/MS in all participants. A subset of 15 patients received oral contraceptive treatment for medical indications and had follow-up hormonal evaluations at 6 months.

Ages

13 to 21 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of PCOS based on Rotterdam criteria * Age between 13 and 21 years * No hormonal treatment in the 3 months prior to study enrollment * Consent provided Exclusion Criteria: * Congenital adrenal hyperplasia * Cushing's syndrome * Pregnancy * Use of hormonal medications within 1 year prior to baseline

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Conditions

The condition(s) this trial relates to.

Hyperandrogenism polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Polycystic ovary syndrome (PCOS)

Contacts and locations

Locations

  • Istanbul University

    Istanbul, 34093, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.