PCOS treatments put to the test: which one protects your heart?
NCT ID NCT06889454
First seen Nov 19, 2025 · Last updated Jun 22, 2026 · Updated 21 times
Summary
This study looks at how different treatments for polycystic ovary syndrome (PCOS) — including a GLP-1 drug, birth control pills, metformin, and lifestyle changes — affect the heart and blood vessels. Researchers will measure changes in heart function and artery stiffness in 120 women with PCOS over six months. The goal is to see which treatment best supports heart health and how it relates to hormone and metabolic issues.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Attikon University General Hospital
RECRUITINGChaïdári, 124 62, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GLP-1 receptor agonist, oral contraceptive, metformin, lifestyle modification
What this could lead to
If successful, this could help doctors choose PCOS treatments that also protect heart health, reducing long-term cardiovascular risks.
What could go wrong
This is an early-stage observational study with only 120 participants, so results may not apply to all women with PCOS. The treatments are already approved, but the specific heart effects are uncertain.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.