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Neck therapy shows promise for headache relief

NCT ID NCT07617051

Symptom relief Sponsor: Jordan University of Science and Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a specific manual therapy technique called Passive Physiological Intervertebral Movements to a standard exercise program provides extra relief for people with cervicogenic headache, a headache that starts from the neck. Sixty-four adults with this condition were split into two groups: one received the manual therapy plus exercise, and the other received exercise alone. Both groups had eight sessions over four weeks, and researchers measured pain, disability, and quality of life right after treatment and again three months later.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Passive Physiological Intervertebral Movements (manual therapy) and Therapeutic Exercise
What this could lead to
If successful, this could point toward a more effective physical therapy approach for cervicogenic headache, potentially reducing pain and improving quality of life.
What could go wrong
This is a small, completed trial with only 64 participants, so results may not apply to everyone. The benefit of adding manual therapy to exercise may be small or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

May 2022

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Were diagnosed with cervicogenic headache using a standardized clinical diagnostic protocol based on history and physical examination. Had a positive Cervical Flexion-Rotation Test, defined as reduced cervical rotation by ≥10° on the symptomatic side compared with the asymptomatic side, or total rotation \<32°. Had referred pain originating from the cervical spine, confirmed by mechanical provocation such as manual palpation or pressure over the C1-C3 zygapophysial joints reproducing typical headache symptoms. Had pain behavior consistent with cervicogenic headache, such as symptoms worsened by sustained neck posture or specific neck movements. Had other primary headache disorders excluded based on clinical history and symptom characteristics. Exclusion Criteria: * Diagnosed with disc herniation and stenosis of the spinal canal. * Clinically diagnosed as a case of cervical radiculopathy or myelopathy. * Subjects with conditions or diseases that are contraindicated for mobilization treatment: rheumatoid arthritis, ankylosing spondylitis, spondylolistheses, cervical fractures, osteoporosis, osteomyelitis, malignancy, and pregnancy * Have received manual therapy or exercise by a physical therapist in the last six months. * Patients diagnosed with cognitive dysfunction, psychological disorder, or communication/cognitive deficits.

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Conditions

The condition(s) this trial relates to.

Neck Pain Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervicogenic headache

Contacts and locations

Locations

  • Jordan University of Science and Technology

    Irbid, 22110, Jordan

More trials for these conditions

Other studies related to the condition(s) this trial covers.