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Sound waves target Parkinson's brain to ease movement problems

NCT ID NCT03319485

Summary

This study is testing whether focused ultrasound can help people with advanced Parkinson's disease who still have severe movement problems despite taking medication. The treatment uses sound waves to create a small, precise lesion in a specific brain area to reduce involuntary movements and motor fluctuations. Participants are adults with medication-resistant Parkinson's who will be randomly assigned to receive either the real ultrasound treatment or a sham procedure for comparison.

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Contacts and locations

Locations

  • Azienda Ospedaliera Universitaria di Verona, Univerista di Verona

    Verona, 37134, Italy

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • CINAC-Hospital HM Puerta del Sur

    Móstoles, Madrid, 28938, Spain

  • Chang Bing Show Chwan Memorial Hospital

    Changhua, Taiwan

  • Clinica Universidad De Navarra

    Pamplona, Navarre, 31008, Spain

  • Fondazione IRCCS Neurological Institute Carlo Besta

    Milan, 20133, Italy

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • New York University Health Langone

    New York, New York, 10016, United States

  • Palm Beach Neuroscience Institute/Sperling Medical Group

    Boynton Beach, Florida, 33472, United States

  • Pennsylvania Hospital Department of Neurosurgery

    Philadelphia, Pennsylvania, 19106, United States

  • Rambam Health Care

    Haifa, 3109601, Israel

  • Severance Hospital, Yonsei University Health System

    Seoul, South Korea

  • St. Mary's Hospital

    London, United Kingdom

  • Stanford University Medical Center

    Stanford, California, 94305, United States

  • Swedish Medical Center

    Seattle, Washington, 98122, United States

  • The Ohio State Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Toronto Western Hospital

    Toronto, Ontario, M5T 2S8, Canada

  • University of Maryland Medical System

    Baltimore, Maryland, 21201, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.