100,000 families join landmark study on parental exposures and child health
NCT ID NCT07514377
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 100,000 Chinese families from before pregnancy through the child's teenage years. Researchers collect health data, biospecimens, and environmental information to understand how parents' exposures affect pregnancy outcomes and child development. The goal is to find ways to prevent health problems across generations.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could identify key windows for intervention to prevent chronic diseases across generations.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Results may take many years and might not apply outside China.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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100,000 people
The number who actually took part.
- Started
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Aug 2025
- Expected to finish
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Dec 2039
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The participants come from 24 survey sites in the northwest, southwest, central, northern, eastern, southern, and northeastern regions, include parental and offspring generations. 1. Parental Generation: Eligible participants include couples of reproductive age who undergo free pre-pregnancy eugenic health examinations, or pregnant women registered for prenatal care at healthcare institutions during early pregnancy (≤14 weeks). 2. Offspring Generation: Newborns whose parents participated in pre-pregnancy eugenic health checks and/or maternal prenatal examinations are enrolled in the cohort upon parental (guardian) consent.
- Ages
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1 day to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Parental Generation: Eligible participants include couples of reproductive age who undergo free pre-pregnancy eugenic health examinations, or pregnant women registered for prenatal care at healthcare institutions during early pregnancy (≤14 weeks). The participants are aged 18-45 years old and have mobile phones and internet (computer) devices. All participants must provide informed consent and commit to long-term follow-up. The participants have no serious neuropsychiatric disorders, with sufficient understanding and expression to complete the survey. 2. Offspring Generation: Newborns whose parents participated in pre-pregnancy eugenic health checks and/or maternal prenatal examinations are enrolled in the cohort upon parental (guardian) consent. Designated hospitals will provide expedited medical services, free physical examinations, free child healthcare, and free psychological counseling to ensure comprehensive follow-up spanning infancy, preschool, school age, and early adolescence (0-14 years). Exclusion Criteria: 1. Intellectual disability or other serious mental disorders; 2. Suffering from serious underlying diseases and may have a significant impact on pregnancy outcome; 3. Those with poor compliance and difficulty in follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Research Institute for Family Planning
Beijing, Beijing Municipality, China
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Other studies related to the condition(s) this trial covers.
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