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Could a diabetes drug and supplements boost chemo for pancreatic cancer?

NCT ID NCT02336087

First seen Feb 04, 2026 · Last updated Jun 13, 2026 · Updated 21 times

Summary

This early-phase trial tests the safety and feasibility of adding the diabetes drug metformin and a specific dietary supplement blend to standard chemotherapy (gemcitabine and Abraxane) for people with pancreatic cancer that cannot be removed by surgery. The study involves 21 participants and aims to see if this combination is tolerable and can slow cancer growth. It is not a cure, but an effort to improve disease control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • City of Hope Rancho Cucamonga

    Rancho Cucamonga, California, 91730, United States

  • City of Hope South Pasadena

    South Pasadena, California, 91030, United States

  • City of Hope West Covina

    West Covina, California, 91790, United States

Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma malignant pancreatic neoplasm pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.