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New surgical technique aims to reduce leftover cancer cells in pancreatic cancer surgery

NCT ID NCT04902352

Knowledge-focused Sponsor: University Hospital Birmingham NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a specific surgical technique (called peri-adventitial dissection) can help surgeons remove all cancer cells during pancreatic cancer surgery. The trial involves 102 adults with non-spreading pancreatic tumors who are having a standard operation called a pancreaticoduodenectomy. The main goal is to see if this technique lowers the chance of cancer cells being left behind at the surgical margin.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 102 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2021

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All adult (≥ 18 years old) patients with a non-metastatic (based on NCCN definition) on imaging pancreatic tumour of the head or uncinate process treated with a pancreaticoduodenectomy Exclusion Criteria: 1. All paediatric patients (\< 18 years old) 2. Patients that cannot provide consent 3. All borderline, locally advanced and metastatic pancreatic tumours on imaging (based on NCCN criteria) 4. All patients with a cytological or histological diagnosis of cholangiocarcinoma, ampullary and duodenal carcinoma 5. All patients with benign disease or dysplasia with no evidence of malignancy

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Conditions

The condition(s) this trial relates to.

pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pancreatic adenocarcinoma

Contacts and locations

Locations

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham, County (Optional), B15 2GW, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.